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. 1987 Aug;99(1):167–172. doi: 10.1017/s0950268800066991

A food-poisoning incident caused by Clostridium botulinum toxin A in Japan.

T Otofuji, H Tokiwa, K Takahashi
PMCID: PMC2249182  PMID: 3301378

Abstract

Food poisoning caused by Clostridium botulinum toxin A occurred in Japan. Eleven (31%) of 36 patients from 14 different areas died of botulism. Most of the patients had eaten commercial fried lotus-rhizome solid mustard without heating. The food, which implicated one of the special local products used for gifts in Kumamoto, was found to have been produced by a manufacturer in Kumamoto prefecture. In Fukuoka prefecture, two of three patients died on days 4 and 8 after eating the food; they had typical symptoms of botulism. A total of 42 packages of the food bought as gifts was collected from different districts in Fukuoka prefecture for examination for both organism and toxin. Thirteen of these (31%) were contaminated with the organism, and in 11 (26%) a small amount of toxin A had been produced.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DUFF J. T., WRIGHT G. G., KLERER J., MOORE D. E., BIBLER R. H. Studies on immunity to toxins of Clostridium botulinum. I. A simplified procedure for isolation of type A toxin. J Bacteriol. 1957 Jan;73(1):42–47. doi: 10.1128/jb.73.1.42-47.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. GERWING J., DOLMAN C. E., BAINS H. S. ISOLATION AND CHARACTERIZATION OF A TOXIC MOIETY OF LOW MOLECULAR WEIGHT FROM CLOSTRIDIUM BOTULINUM TYPE A. J Bacteriol. 1965 May;89:1383–1386. doi: 10.1128/jb.89.5.1383-1386.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Sakaguchi G., Sakaguchi S., Kondo H. Rapid bioassay for Clostridium botulinum type-E toxins by intravenous injection into mice. Jpn J Med Sci Biol. 1968 Dec;21(6):369–378. doi: 10.7883/yoken1952.21.369. [DOI] [PubMed] [Google Scholar]

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