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. 1987 Oct;99(2):295–306. doi: 10.1017/s0950268800067777

Salmonella serotypes and incidence of multiply-resistant Salmonellae isolated from diarrhoeal patients in Hong Kong from 1973-82.

J Ling 1, P Y Chau 1, B Rowe 1
PMCID: PMC2249276  PMID: 3678394

Abstract

Salmonella was the most frequent bacterial pathogen isolated from patients with acute diarrhoea in Hong Kong. In Queen Mary Hospital, the major hospital on Hong Kong Island, 94.7% of salmonellae isolated from faecal specimens from patients during the period 1973-82 belonged to the gastroenteric group, while 5.3% belonged to the enteric fever group. Amongst the gastroenteric group, 68 salmonella serotypes were identified, with Salmonella derby, S. typhimurium and S. anatum being the predominant ones. Three outbreaks caused by S. johannesburg, S. worthington and S. wandsworth were detected. Of S. typhimurium, 61.6% were resistant to multiple antibiotics and belonged to four major phage types: 193, 22, 138 and U288. The majority (96.8%) of S. johannesburg strains which caused a widespread epidemic were multiply-resistant. Multiple antibiotic resistance was rarely observed in most other gastroenteric salmonellae. S. typhi was the commonest of the enteric fever group isolated from the blood of patients. Nineteen phage types were identified; E1 being the commonest (18.5%) while 21% were nontypable. Many of these isolated were resistant to streptomycin or sulphadiazine, but none were resistant to ampicillin, chloramphenicol or trimethoprim.

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Selected References

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  1. ANDERSON E. S., DATTA N. RESISTANCE TO PENICILLINS AND ITS TRANSFER IN ENTEROBACTERIACEAE. Lancet. 1965 Feb 20;1(7382):407–409. doi: 10.1016/s0140-6736(65)90004-8. [DOI] [PubMed] [Google Scholar]
  2. ANDERSON E. S., WILLIAMS R. E. Bacteriophage typing of enteric pathogens and staphylococci and its use in epidemiology. J Clin Pathol. 1956 May;9(2):94–127. doi: 10.1136/jcp.9.2.94. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Barker R., Old D. C., Sharp J. C. Phage type/biotype groups of Salmonella typhimurium in Scotland 1974-6: variation during spread of epidemic clones. J Hyg (Lond) 1980 Feb;84(1):115–125. doi: 10.1017/s0022172400026607. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
  5. CALLOW B. R. A new phage-typing scheme for Salmonella typhi-murium. J Hyg (Lond) 1959 Sep;57:346–359. doi: 10.1017/s0022172400020209. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Centers for Disease Control (CDC) Human Salmonella isolates--United States, 1983. MMWR Morb Mortal Wkly Rep. 1984 Dec 14;33(49):693–695. [PubMed] [Google Scholar]
  7. Chau P. Y., Huang C. T. A one-day selective migration procedure for detecting salmonellae in faeces. J Clin Pathol. 1974 May;27(5):405–407. doi: 10.1136/jcp.27.5.405. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Chau P. Y., Huang C. T. Salmonellosis in Hong Kong. Public Health. 1977 Mar;91(2):83–89. doi: 10.1016/s0033-3506(77)80005-x. [DOI] [PubMed] [Google Scholar]
  9. Chau P. Y., Ling J., Threlfall E. J., Im S. W. Genetic instability of R plasmids in relation to the shift of drug resistance patterns in Salmonella johannesburg. J Gen Microbiol. 1982 Feb;128(2):239–245. doi: 10.1099/00221287-128-2-239. [DOI] [PubMed] [Google Scholar]
  10. Chau P. Y., Shortridge K. F., Huang C. T. Salmonella in pig carcasses for human consumption in Hong Kong: a study on the mode of contamination. J Hyg (Lond) 1977 Apr;78(2):253–260. doi: 10.1017/s002217240005614x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Chau P. Y., Wong W. T., Fok Y. P. Resistance to chloramphenicol and ampicillin Salmonella johannesburg in Hong Kong: observations over a five-year period 1973-1977. J Hyg (Lond) 1978 Dec;81(3):343–351. doi: 10.1017/s0022172400025225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Cherubin C. E. Antibiotic resistance of Salmonella in Europe and the United States. Rev Infect Dis. 1981 Nov-Dec;3(6):1105–1126. doi: 10.1093/clinids/3.6.1105. [DOI] [PubMed] [Google Scholar]
  13. Frost J. A., Rowe B., Ward L. R., Threlfall E. J. Characterization of resistance plasmids and carried phages in an epidemic clone of multi-resistant Salmonella typhimurium in India. J Hyg (Lond) 1982 Apr;88(2):193–204. doi: 10.1017/s0022172400070066. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. HUANG C. T., CHAN-TOEH C. H. SALMONELLA SEROTYPES ISOLATED IN HONG KONG. J Trop Med Hyg. 1964 Apr;67:95–99. [PubMed] [Google Scholar]
  15. Hepner E. Food poisoning and salmonella infections in England and Wales, 1976--1978. An analysis of reports to the Communicable Disease Surveillance Centre of the Public Health Laboratory Service. Public Health. 1980 Nov;94(6):337–349. doi: 10.1016/s0033-3506(80)80136-3. [DOI] [PubMed] [Google Scholar]
  16. Im S. W., Chow K., Chau P. Y. Rectal thermometer mediated cross-infection with Salmonella wandsworth in a paediatric ward. J Hosp Infect. 1981 Jun;2(2):171–174. doi: 10.1016/0195-6701(81)90026-8. [DOI] [PubMed] [Google Scholar]
  17. Ip H. M., Sin W. K., Chau P. Y., Tse D., Teoh-Chan C. H. Neonatal infection due to Salmonella worthington transmitted by a delivery-room suction apparatus. J Hyg (Lond) 1976 Dec;77(3):307–314. doi: 10.1017/s0022172400055650. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Jegathesan M. Salmonella serotypes isolated from man in Malaysia over the 10-year period 1973-1982. J Hyg (Lond) 1984 Jun;92(3):395–399. doi: 10.1017/s0022172400064615. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Ling J., Chau P. Y. Incidence of plasmids in multiply-resistant Salmonella isolates from diarrhoeal patients in Hong Kong from 1973-82. Epidemiol Infect. 1987 Oct;99(2):307–321. doi: 10.1017/s0950268800067789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Manten A., Guinée P. A., Kampelmacher E. H., Voogd C. E. An eleven-year study of drug resistance in Salmonella in the Netherlands. Bull World Health Organ. 1971;45(1):85–93. [PMC free article] [PubMed] [Google Scholar]
  21. Neu H. C., Cherubin C. E., Longo E. D., Flouton B., Winter J. Antimicrobial resistance and R-factor transfer among isolates of Salmonella in the northeastern United States: a comparison of human and animal isolates. J Infect Dis. 1975 Dec;132(6):617–622. doi: 10.1093/infdis/132.6.617. [DOI] [PubMed] [Google Scholar]
  22. Teoh-Chan C. H., Chau P. Y., Tse D., Sin W. K., Ip H. M., Lan R. Hospital Salmonella johannesburg infection and its possible role in the community spread of the infection in Hong Kong. J Hyg (Lond) 1977 Feb;78(1):113–119. doi: 10.1017/s0022172400055996. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Threlfall E. J., Ward L. R., Rowe B. Epidermic spread of a chloramphenicol-resistant strain of Salmonella typhimurium phage type 204 in bovine animals in Britain. Vet Rec. 1978 Nov 11;103(20):438–440. doi: 10.1136/vr.103.20.438. [DOI] [PubMed] [Google Scholar]
  24. Threlfall E. J., Ward L. R., Rowe B. Spread of multiresistant strains of Salmonella typhimurium phage types 204 and 193 in Britain. Br Med J. 1978 Oct 7;2(6143):997–997. doi: 10.1136/bmj.2.6143.997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Turnbull P. C. Food poisoning with special reference to Salmonella -- its epidemiology, pathogenesis and control. Clin Gastroenterol. 1979 Sep;8(3):663–714. [PubMed] [Google Scholar]
  26. Vernon E. Food poisoning and salmonella infections in England and Wales, 1973-75. An analysis of reports to the Public Health Laboratory Service. Public Health. 1977 Sep;91(5):225–235. doi: 10.1016/s0033-3506(77)80051-6. [DOI] [PubMed] [Google Scholar]
  27. Voogd C. E., van Leeuwen W. J., Guinée P. A., Manten A., Valkenburg J. J. Incidence of resistance to ampicillin, chloramphenicol, kanamycin and tetracycline among Salmonella species isolated in the Netherlands in 1972, 1973 and 1974. Antonie Van Leeuwenhoek. 1977;43(3-4):269–281. doi: 10.1007/BF02313755. [DOI] [PubMed] [Google Scholar]

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