Skip to main content
NCBI home page
Epidemiology and Infection logoLink to Epidemiology and Infection
. 1987 Oct;99(2):455–462. doi: 10.1017/s0950268800067959

Analysis of penicillinase-producing Neisseria gonorrhoeae isolates in Madrid (Spain) from 1983-85.

A Fenoll 1, S Berrón 1, J A Vázquez 1
PMCID: PMC2249288  PMID: 2960555

Abstract

Between April 1983 and December 1985, 576 strains of Neisseria gonorrhoeae were isolated in our laboratory from patients attending Sexually Transmitted Diseases (STD) clinics. Of these, 61 (10.6%) were penicillinase-producing. Studies on these strains by plasmid analysis, auxotyping and serogrouping showed that the predominant type strains harboured the Asian resistance plasmid, were prototrophic, and were of serogroup W II/W III. About half of the strains, both of the African and Asian type, harboured the transfer plasmid. Strains of serogroup W II/W III were less sensitive to tetracycline and cefoxitin than serogroup W I strains.

Full text

PDF
455

Images in this article

460Fig. 2
on p.460

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ansink-Schipper M. C., Huikeshoven M. H., Woudstra R. K., van Klingeren B., de Koning G. A., Tio D., Schoonhoven F. J., Coutinho R. A. Epidemiology of PPNG infections in Amsterdam: analysis by auxanographic typing and plasmid characterisation. Br J Vener Dis. 1984 Feb;60(1):23–28. doi: 10.1136/sti.60.1.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ansink-Schipper M. C., van Klingeren B., Huikeshoven M. H., Woudstra R. K., Dessens-Kroon M., van Wijngaarden L. J. Epidemiology of PPNG infections in the Netherlands: analysis by auxanographic typing and plasmid identification. Br J Vener Dis. 1984 Jun;60(3):141–146. doi: 10.1136/sti.60.3.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Arya O. P., Rees E., Turner G. C., Percival A., Bartzokas C. A., Annels E. H., Carey P. B., Ghosh A. K., Jephcott A. E., Johnston N. A. Epidemiology of penicillinase-producing Neisseria gonorrhoeae in Liverpool from 1977 to 1982. J Infect. 1984 Jan;8(1):70–83. doi: 10.1016/s0163-4453(84)93462-5. [DOI] [PubMed] [Google Scholar]
  4. Birnboim H. C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 1979 Nov 24;7(6):1513–1523. doi: 10.1093/nar/7.6.1513. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bygdeman S., Bäckman M., Danielsson D., Norgren M. Genetic linkage between serogroup specificity and antibiotic resistance in Neisseria gonorrhoeae. Acta Pathol Microbiol Immunol Scand B. 1982 Jun;90(3):243–250. doi: 10.1111/j.1699-0463.1982.tb00112.x. [DOI] [PubMed] [Google Scholar]
  6. Centers for Disease Control (CDC) Spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae. MMWR Morb Mortal Wkly Rep. 1983 Feb 4;32(4):51–52. [PubMed] [Google Scholar]
  7. Danielsson D., Bygdeman S., Kallings I. Epidemiology of gonorrhoea: serogroup, antibiotic susceptibility and auxotype patterns of consecutive gonococcal isolates from ten different areas of Sweden. Scand J Infect Dis. 1983;15(1):33–42. doi: 10.3109/inf.1983.15.issue-1.07. [DOI] [PubMed] [Google Scholar]
  8. Goh B. T., Rodin P., Johnston N. A., Wong H. H. Penicillinase-producing Neisseria gonorrhoeae: epidemiology, antimicrobial susceptibility and plasmid types. J Infect. 1985 Jul;11(1):63–69. doi: 10.1016/s0163-4453(85)91094-1. [DOI] [PubMed] [Google Scholar]
  9. Macrina F. L., Kopecko D. J., Jones K. R., Ayers D. J., McCowen S. M. A multiple plasmid-containing Escherichia coli strain: convenient source of size reference plasmid molecules. Plasmid. 1978 Jun;1(3):417–420. doi: 10.1016/0147-619x(78)90056-2. [DOI] [PubMed] [Google Scholar]
  10. Meyers J. A., Sanchez D., Elwell L. P., Falkow S. Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid. J Bacteriol. 1976 Sep;127(3):1529–1537. doi: 10.1128/jb.127.3.1529-1537.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Perine P. L., Thornsberry C., Schalla W., Biddle J., Siegel M. S., Wong K. H., Thompson S. E. Evidence for two distinct types of penicillinase-producing Neisseria gonorrhoeae. Lancet. 1977 Nov 12;2(8046):993–995. doi: 10.1016/s0140-6736(77)92891-4. [DOI] [PubMed] [Google Scholar]
  12. Pon E., Batchelor R. A., Howell H. B., Blakley K. G., Lake J., Rice R. J., Biddle J. W., Conwill D. E. An unusual case of penicillinase-producing Neisseria gonorrhoeae resistant to spectinomycin in California. Sex Transm Dis. 1986 Jan-Mar;13(1):47–49. doi: 10.1097/00007435-198601000-00010. [DOI] [PubMed] [Google Scholar]
  13. Vázquez J., Fenoll A., Berrón S., Téllez A., Bilbao R. Penicillinase producing strains of Neisseria gonorrhoeae in Madrid. Genitourin Med. 1985 Apr;61(2):139–139. doi: 10.1136/sti.61.2.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. WHITE L. A., KELLOGG D. S., Jr NEISSERIA GONORRHOEAE IDENTIFICATION IN DIRECT SMEARS BY A FLUORESCENT ANTIBODY-COUNTERSTAIN METHOD. Appl Microbiol. 1965 Mar;13:171–174. doi: 10.1128/am.13.2.171-174.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Yvert F., Frost E., Guibourdenche M., Riou J. Y., Ivanoff B. Auxotypes and serogroups of penicillinase producing and non-producing strains of Neisseria gonorrhoeae isolated in Franceville, Gabon. Genitourin Med. 1985 Apr;61(2):99–102. doi: 10.1136/sti.61.2.99. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Epidemiology and Infection are provided here courtesy of Cambridge University Press

RESOURCES