Skip to main content
NCBI home page
Epidemiology and Infection logoLink to Epidemiology and Infection
. 1987 Oct;99(2):407–412. doi: 10.1017/s0950268800067893

Invasive nosocomial pulmonary aspergillosis: risk factors and hospital building works.

M Perraud 1, M A Piens 1, N Nicoloyannis 1, P Girard 1, M Sepetjan 1, J P Garin 1
PMCID: PMC2249302  PMID: 3678402

Abstract

A retrospective epidemiological study of 22 observations of invasive pulmonary aspergillosis, of which 18 were fatal, occurring over a period of 30 months, implicated certain building sites within the hospital. The building works were responsible for the diffusion into the atmosphere of fungal spores from normally closed reservoirs, notably false ceilings, fibrous thermal and/or acoustic insulation materials and roller-blind casings. The results of our study permit us to suggest that protective measures should be set up or that immunodepressed patients are evacuated when such works are to be carried out in an in-patient establishment.

Full text

PDF
407

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aisner J., Schimpff S. C., Bennett J. E., Young V. M., Wiernik P. H. Aspergillus infections in cancer patients. Association with fireproofing materials in a new hospital. JAMA. 1976 Jan 26;235(4):411–412. [PubMed] [Google Scholar]
  2. Arnow P. M., Andersen R. L., Mainous P. D., Smith E. J. Pumonary aspergillosis during hospital renovation. Am Rev Respir Dis. 1978 Jul;118(1):49–53. doi: 10.1164/arrd.1978.118.1.49. [DOI] [PubMed] [Google Scholar]
  3. Burton J. R., Zachery J. B., Bessin R., Rathbun H. K., Greenough W. B., 3rd, Sterioff S., Wright J. R., Slavin R. E., Williams G. M. Aspergillosis in four renal transplant recipients. Diagnosis and effective treatment with amphotericin B. Ann Intern Med. 1972 Sep;77(3):383–388. doi: 10.7326/0003-4819-77-3-383. [DOI] [PubMed] [Google Scholar]
  4. Krick J. A., Remington J. S. Opportunistic invasive fungal infections in patients with leukaemia lymphoma. Clin Haematol. 1976 Jun;5(2):249–310. [PubMed] [Google Scholar]
  5. Leclerc P., Capron F., de Fenoyl O., Bientz M., Rochemaure J. Pneumopathies infectieuses de l'immunosuppression. Poumon Coeur. 1982 Mar-Apr;38(2):101–110. [PubMed] [Google Scholar]
  6. Lentino J. R., Rosenkranz M. A., Michaels J. A., Kurup V. P., Rose H. D., Rytel M. W. Nosocomial aspergillosis: a retrospective review of airborne disease secondary to road construction and contaminated air conditioners. Am J Epidemiol. 1982 Sep;116(3):430–437. doi: 10.1093/oxfordjournals.aje.a113427. [DOI] [PubMed] [Google Scholar]
  7. Mahoney D. H., Jr, Steuber C. P., Starling K. A., Barrett F. F., Goldberg J., Fernbach D. J. An outbreak of aspergillosis in children with acute leukemia. J Pediatr. 1979 Jul;95(1):70–72. doi: 10.1016/s0022-3476(79)80086-4. [DOI] [PubMed] [Google Scholar]
  8. Prystowsky S. D., Vogelstein B., Ettinger D. S., Merz W. G., Kaizer H., Sulica V. I., Zinkham W. H. Invasive aspergillosis. N Engl J Med. 1976 Sep 16;295(12):655–658. doi: 10.1056/NEJM197609162951206. [DOI] [PubMed] [Google Scholar]
  9. Rose H. D. Mechanical control of hospital ventilation and Aspergillus infections. Am Rev Respir Dis. 1972 Feb;105(2):306–307. doi: 10.1164/arrd.1972.105.2.306. [DOI] [PubMed] [Google Scholar]
  10. Sarubbi F. A., Jr, Kopf H. B., Wilson M. B., McGinnis M. R., Rutala W. A. Increased recovery of Aspergillus flavus from respiratory specimens during hospital construction. Am Rev Respir Dis. 1982 Jan;125(1):33–38. doi: 10.1164/arrd.1982.125.1.33. [DOI] [PubMed] [Google Scholar]
  11. Sayer W. J., Shean D. B., Ghosseiri J. Estimation of airborne fungal flora by the Andersen sampler versus the gravity settling culture plate. 1. Isolation frequency and numbers of colonies. J Allergy. 1969 Oct;44(4):214–227. doi: 10.1016/0021-8707(69)90088-4. [DOI] [PubMed] [Google Scholar]
  12. Streifel A. J., Lauer J. L., Vesley D., Juni B., Rhame F. S. Aspergillus fumigatus and other thermotolerant fungi generated by hospital building demolition. Appl Environ Microbiol. 1983 Aug;46(2):375–378. doi: 10.1128/aem.46.2.375-378.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Epidemiology and Infection are provided here courtesy of Cambridge University Press

RESOURCES