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. 1988 Jun;100(3):501–510. doi: 10.1017/s0950268800067236

Protection against experimental infection with influenza virus A/equine/Miami/63 (H3N8) provided by inactivated whole virus vaccines containing homologous virus.

J A Mumford 1, J M Wood 1, C Folkers 1, G C Schild 1
PMCID: PMC2249356  PMID: 2837409

Abstract

Thirty-one ponies immunized with inactivated virus vaccine containing A/equine/Miami/63 (H3N8) virus and six seronegative ponies were experimentally challenged with the homologous virus strain. All 6 unvaccinated ponies and 11 out of 31 vaccinated ponies became infected. A clear relationship between pre-challenge antibody, measured by single radial haemolysis (SRH), and protection was demonstrated as judged by virus excretion, febrile responses and antibody responses. Those ponies with SRH antibody levels greater than 74 mm2 were completely protected against challenge infection by the intranasal route.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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