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. 1968 Aug;60(4):1479–1486. doi: 10.1073/pnas.60.4.1479

Inhibition of formylmethionyl-transfer RNA binding to ribosomes by tetracycline.

S Sarkar, R E Thach
PMCID: PMC224944  PMID: 5244755

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARLINGHAUS R., SHAEFER J., SCHWEET R. MECHANISM OF PEPTIDE BOND FORMATION IN POLYPEPTIDE SYNTHESIS. Proc Natl Acad Sci U S A. 1964 Jun;51:1291–1299. doi: 10.1073/pnas.51.6.1291. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Allende J. E., Weissbach H. GTP interaction with a protein synthesis initiation factor preparation from Escherichia coli. Biochem Biophys Res Commun. 1967 Jul 10;28(1):82–88. doi: 10.1016/0006-291x(67)90410-x. [DOI] [PubMed] [Google Scholar]
  3. Anderson J. S., Bretscher M. S., Clark B. F., Marcker K. A. A GTP requirement for binding initiator tRNA to ribosomes. Nature. 1967 Jul 29;215(5100):490–492. doi: 10.1038/215490a0. [DOI] [PubMed] [Google Scholar]
  4. Cundliffe E., McQuillen K. Bacterial protein synthesis: the effects of antibiotics. J Mol Biol. 1967 Nov 28;30(1):137–146. doi: 10.1016/0022-2836(67)90249-5. [DOI] [PubMed] [Google Scholar]
  5. Gottesman M. E. Reaction of ribosome-bound peptidyl transfer ribonucleic acid with aminoacyl transfer ribonucleic acid or puromycin. J Biol Chem. 1967 Dec 10;242(23):5564–5571. [PubMed] [Google Scholar]
  6. HIEROWSKI M. INHIBITION OF PROTEIN SYNTHESIS BY CHLORTETRACYCLINE IN THE E. COLI IN VITRO SYSTEM. Proc Natl Acad Sci U S A. 1965 Mar;53:594–599. doi: 10.1073/pnas.53.3.594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Heintz R., McAllister H., Arlinghaus R., Schweet R. Formation and function of the active ribosome complex. Cold Spring Harb Symp Quant Biol. 1966;31:633–639. doi: 10.1101/sqb.1966.031.01.082. [DOI] [PubMed] [Google Scholar]
  8. Hershey J. W., Monro R. E. A competitive inhibitor of the GTP reaction in protein synthesis. J Mol Biol. 1966 Jun;18(1):68–76. doi: 10.1016/s0022-2836(66)80077-3. [DOI] [PubMed] [Google Scholar]
  9. Hershey J. W., Thach R. E. Role of guanosine 5'-triphosphate in the initiation of Peptide synthesis, I. Synthesis of formylmethionyl-puromycin. Proc Natl Acad Sci U S A. 1967 Mar;57(3):759–766. doi: 10.1073/pnas.57.3.759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Igarashi K., Kaji A. On the nature of two ribosomal sites for specific sRNA binding. Proc Natl Acad Sci U S A. 1967 Nov;58(5):1971–1976. doi: 10.1073/pnas.58.5.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. KAJI H., KAJI A. SPECIFIC BINDING OF SRNA WITH THE TEMPLATE-RIBOSOME COMPLEX. Proc Natl Acad Sci U S A. 1964 Dec;52:1541–1547. doi: 10.1073/pnas.52.6.1541. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Leder P., Bursztyn H. Initiation of protein synthesis II. A convenient assay for the ribosome-dependent synthesis of N-formyl-C14-methionylpuromycin. Biochem Biophys Res Commun. 1966 Oct 20;25(2):233–238. doi: 10.1016/0006-291x(66)90586-9. [DOI] [PubMed] [Google Scholar]
  13. Leder P., Nau M. M. Initiation of protein synthesis. 3. Factor-GTP-codon-dependent binding of F-met-tRNA to ribosomes. Proc Natl Acad Sci U S A. 1967 Aug;58(2):774–781. doi: 10.1073/pnas.58.2.774. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Lucas-Lenard J., Haenni A. L. Requirement of granosine 5'-triphosphate for ribosomal binding of aminoacyl-SRNA. Proc Natl Acad Sci U S A. 1968 Feb;59(2):554–560. doi: 10.1073/pnas.59.2.554. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Monro R. E., Marcker K. A. Ribosome-catalysed reaction of puromycin with a formylmethionine-containing oligonucleotide. J Mol Biol. 1967 Apr 28;25(2):347–350. doi: 10.1016/0022-2836(67)90146-5. [DOI] [PubMed] [Google Scholar]
  16. Mukundan M. A., Hershey J. W., Dewey K. F., Thach R. E. Binding of formylmethionyl-tRNA to 30S ribosomal sub-units. Nature. 1968 Mar 16;217(5133):1013–1016. doi: 10.1038/2171013a0. [DOI] [PubMed] [Google Scholar]
  17. NIRENBERG M., LEDER P. RNA CODEWORDS AND PROTEIN SYNTHESIS. THE EFFECT OF TRINUCLEOTIDES UPON THE BINDING OF SRNA TO RIBOSOMES. Science. 1964 Sep 25;145(3639):1399–1407. doi: 10.1126/science.145.3639.1399. [DOI] [PubMed] [Google Scholar]
  18. Nakamoto T. The initial phase in the polyuridylic acid-directed polymerization of phenylalanine. J Biol Chem. 1967 Oct 10;242(19):4534–4537. [PubMed] [Google Scholar]
  19. Ohta T., Sarkar S., Thach R. E. The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes. Proc Natl Acad Sci U S A. 1967 Oct;58(4):1638–1644. doi: 10.1073/pnas.58.4.1638. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Ravel J. M. Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomes. Proc Natl Acad Sci U S A. 1967 Jun;57(6):1811–1816. doi: 10.1073/pnas.57.6.1811. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Seeds N. W., Retsema J. A., Conway T. W. Properties of ribosomal binding sites for phenylalanyl-transfer ribonucleic acid. J Mol Biol. 1967 Aug 14;27(3):421–430. doi: 10.1016/0022-2836(67)90048-4. [DOI] [PubMed] [Google Scholar]
  22. Suzuka I., Kaji H., Kaji A. Binding of specific sRNA to 30S ribosomal subunits: effect of 50S ribosomal subunits. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1483–1490. doi: 10.1073/pnas.55.6.1483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. TRAUT R. R., MONRO R. E. THE PUROMYCIN REACTION AND ITS RELATION TO PROTEIN SYNTHESIS. J Mol Biol. 1964 Oct;10:63–72. doi: 10.1016/s0022-2836(64)80028-0. [DOI] [PubMed] [Google Scholar]
  24. Thach R. E., Dewey K. F., Mykolajewycz N. Role of guanosine 5'-triphosphate in the initiation of peptide synthesis, II. Synthesis of dipeptides. Proc Natl Acad Sci U S A. 1967 Apr;57(4):1103–1109. doi: 10.1073/pnas.57.4.1103. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Vazquez D., Monro R. E. Effects of some inhibitors of protein synthesis on the binding of aminoacyl tRNA to ribosomal subunits. Biochim Biophys Acta. 1967 Jun 20;142(1):155–173. doi: 10.1016/0005-2787(67)90524-2. [DOI] [PubMed] [Google Scholar]
  26. WARNER J. R., RICH A. THE NUMBER OF SOLUBLE RNA MOLECULES ON RETICULOCYTE POLYRIBOSOMES. Proc Natl Acad Sci U S A. 1964 Jun;51:1134–1141. doi: 10.1073/pnas.51.6.1134. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Zamir A., Leder P., Elson D. A ribosome-catalyzed reaction between N-formylmethionyl-trna and puromycin. Proc Natl Acad Sci U S A. 1966 Dec;56(6):1794–1801. doi: 10.1073/pnas.56.6.1794. [DOI] [PMC free article] [PubMed] [Google Scholar]

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