Skip to main content
Epidemiology and Infection logoLink to Epidemiology and Infection
. 1989 Jun;102(3):467–471. doi: 10.1017/s0950268800030181

The production of Clostridium botulinum toxin in mammalian, avian and piscine carrion.

G R Smith 1, A Turner 1
PMCID: PMC2249455  PMID: 2661255

Abstract

Mice, birds (chicks, quail) and fish (rudd, goldfish) killed shortly after receiving 1300-2000 spores of Clostridium botulinum per os were incubated, usually at 23 degrees C for 7 days. A 10% (w/v) homogenate of each rotting carcass was then prepared, sterilized by membrane filtration, and assayed for toxin. In mouse carcasses a type C strain of C. botulinum usually produced greater than 2 X 10(5) mouse intraperitoneal LD/g; in fish carcasses it usually produced less--often much less--than 2 X 10(4) LD/g. Avian carcasses appeared to be intermediate between those of mice and fish in their ability to support toxigenesis. A type E strain of C. botulinum, unlike type C, produced toxin equally well in fish and mouse carrion, usually at a concentration of between 2 X 10(4) and 2 X 10(5) LD/g.

Full text

PDF
467

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Huss H. H., Eskildsen U. Botulism in farmed trout caused by Clostridium botulinum type E; a preliminary report. Nord Vet Med. 1974 Dec;26(12):733–738. [PubMed] [Google Scholar]
  2. Monheimer R. H. The relationship of Lake Michigan waterbird mortalities to naturally occurring Clostridium botulinum type E toxin. Wildl Dis. 1968 Jul;4(3):81–85. doi: 10.7589/0090-3558-4.3.81. [DOI] [PubMed] [Google Scholar]
  3. Smart J. L., Jones T. O., Clegg F. G., McMurtry M. J. Poultry waste associated type C botulism in cattle. Epidemiol Infect. 1987 Feb;98(1):73–79. doi: 10.1017/s0950268800061720. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Smith G. R., Turner A. Factors affecting the toxicity of rotting carcasses containing Clostridium botulinum type C. Epidemiol Infect. 1987 Jun;98(3):345–351. doi: 10.1017/s0950268800062105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Smith G. R., Turner A., Till D. Factors affecting the toxicity of rotting carcasses containing Clostridium botulinum type E. Epidemiol Infect. 1988 Jun;100(3):399–405. doi: 10.1017/s0950268800067157. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Epidemiology and Infection are provided here courtesy of Cambridge University Press

RESOURCES