Skip to main content
PMC home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1968 Jun;60(2):668–674. doi: 10.1073/pnas.60.2.668

Reduction and specific alkylation of the receptor for acetylcholine.

A Karlin, M Winnik
PMCID: PMC225098  PMID: 5248823

Full text

PDF
668

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CLELAND W. W. DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS. Biochemistry. 1964 Apr;3:480–482. doi: 10.1021/bi00892a002. [DOI] [PubMed] [Google Scholar]
  2. Changeux J. P., Podleski T. R. On the excitability and cooperativity of the electroplax membrane. Proc Natl Acad Sci U S A. 1968 Mar;59(3):944–950. doi: 10.1073/pnas.59.3.944. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Changeux J. P., Podleski T. R., Wofsy L. Affinity labeling of the acetylcholine-receptor. Proc Natl Acad Sci U S A. 1967 Nov;58(5):2063–2070. doi: 10.1073/pnas.58.5.2063. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. ELLMAN G. L. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959 May;82(1):70–77. doi: 10.1016/0003-9861(59)90090-6. [DOI] [PubMed] [Google Scholar]
  5. FURCHGOTT R. F. Dibenamine blockade in strips of rabbit aorta and its use in differentiating receptors. J Pharmacol Exp Ther. 1954 Jul;111(3):265–284. [PubMed] [Google Scholar]
  6. Gill E. W., Rang H. P. An alkylating derivative of benzilylcholine with specific and long-lasting parasympatholytic activity. Mol Pharmacol. 1966 Jul;2(4):284–297. [PubMed] [Google Scholar]
  7. Gorin G., Martic P. A., Doughty G. Kinetics of the reaction of N-ethylmaleimide with cysteine and some congeners. Arch Biochem Biophys. 1966 Sep 9;115(3):593–597. doi: 10.1016/0003-9861(66)90079-8. [DOI] [PubMed] [Google Scholar]
  8. Karlin A., Bartels E. Effects of blocking sulfhydryl groups and of reducing disulfide bonds on the acetylcholine-activated permeability system of the electroplax. Biochim Biophys Acta. 1966 Nov 8;126(3):525–535. doi: 10.1016/0926-6585(66)90010-0. [DOI] [PubMed] [Google Scholar]
  9. Karlin A. Chemical distinctions between acetylcholinesterase and the acetylcholine receptor. Biochim Biophys Acta. 1967 Jul 11;139(2):358–362. doi: 10.1016/0005-2744(67)90039-3. [DOI] [PubMed] [Google Scholar]
  10. Karlin A. On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine. J Theor Biol. 1967 Aug;16(2):306–320. doi: 10.1016/0022-5193(67)90011-2. [DOI] [PubMed] [Google Scholar]
  11. Karlin A. Permeability and internal concentration of ions during depolarization of the electroplax. Proc Natl Acad Sci U S A. 1967 Sep;58(3):1162–1167. doi: 10.1073/pnas.58.3.1162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Kress L. F., Laskowski M., Sr The basic trypsin inhibitor of bovine pancreas. VII. Reduction with borohydride of disulfide bond linking half-cystine residues 14 and 38. J Biol Chem. 1967 Nov 10;242(21):4925–4929. [PubMed] [Google Scholar]
  13. Light A., Sinha N. K. Difference in the chemical reactivity of the disulfide bonds of trypsin and chymotrypsin. J Biol Chem. 1967 Mar 25;242(6):1358–1359. [PubMed] [Google Scholar]
  14. Mautner H. G., Bartels E., Webb G. D. Sulfur and selenium isologs related to acetycholine. and choline IV. Activity in the electroplax preparation. Biochem Pharmacol. 1966 Feb;15(2):187–193. doi: 10.1016/0006-2952(66)90059-1. [DOI] [PubMed] [Google Scholar]
  15. Neurath H., Walsh K. A., Winter W. P. Evolution of structure and function of proteases. Science. 1967 Dec 29;158(3809):1638–1644. doi: 10.1126/science.158.3809.1638. [DOI] [PubMed] [Google Scholar]
  16. Podleski T. R., Nachmansohn D. Similarities between active sites of acetylcholine receptor and acetylcholinesterase tested with quinolinium ions. Proc Natl Acad Sci U S A. 1966 Sep;56(3):1034–1039. doi: 10.1073/pnas.56.3.1034. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. SCHOFFENIELS E. An isolated single electroplax preparation. II. Improved preparation for studying ion flux. Biochim Biophys Acta. 1957 Dec;26(3):585–596. doi: 10.1016/0006-3002(57)90106-3. [DOI] [PubMed] [Google Scholar]
  18. Singer S. J. Covalent labeling of active sites. Adv Protein Chem. 1967;22:1–54. doi: 10.1016/s0065-3233(08)60040-6. [DOI] [PubMed] [Google Scholar]
  19. Stryer L., Holmgren A., Reichard P. Thioredoxin. A localized conformational change accompanying reduction of the protein to the sulfhydryl form. Biochemistry. 1967 Apr;6(4):1016–1020. doi: 10.1021/bi00856a009. [DOI] [PubMed] [Google Scholar]
  20. TAKEUCHI A., TAKEUCHI N. On the permeability of end-plate membrane during the action of transmitter. J Physiol. 1960 Nov;154:52–67. doi: 10.1113/jphysiol.1960.sp006564. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Volle R. L. Blockade by hexamethonium of drug-induced neuromuscular facilitation. Arch Int Pharmacodyn Ther. 1967 May;167(1):1–9. [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES