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. 1995 Apr;114(2):249–255. doi: 10.1017/s0950268800057915

Epidemic cholera in rural El Salvador: risk factors in a region covered by a cholera prevention campaign

R E Quick, B L Thompson, A Zuniga, G Dominguez, E L De Brizuela, O De Palma, S Almeida, A Valencia, A A Ries, N H Bean, P A Blake
PMCID: PMC2271272  PMID: 7705488

Abstract

In response to the Latin American cholera epidemic, El Salvador began a prevention programme in April 1991. The first case was confirmed in August, and 700 cases were reported within 3 months. A matched case-control study was conducted in rural La Libertad Department in November 1991. Illness was associated with eating cold cooked or raw seafood (odds ratio [OR] = 7·0; 95% confidence limits [CL] = 1·4, 35·0) and with drinking water outside the home (OR = 8·8; 95% CL = 1·7, 44·6). Assertion of knowledge about how to prevent cholera (OR = 0·2; 95% CL = 0·1, 0·8) and eating rice (OR = 0·2; 95% CL = 0·1, 0·8) were protective. More controls than patients regularly used soap (OR = 0·3; 95% CL = 0·1, 1·0). This study demonstrated three important points for cholera prevention: (1) seafood should be eaten cooked and hot; (2) populations at risk should be taught to treat household drinking water and to avoid drinking water outside the home unless it is known to be treated; and (3) education about hygiene can be an important tool in preventing cholera.

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Selected References

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  1. Baine W. B., Mazzotti M., Greco D., Izzo E., Zampieri A., Angioni G., Di Gioia M., Gangarosa E. J., Pocchiari F. Epidemiology of cholera in Italy in 1973. Lancet. 1974 Dec 7;2(7893):1370–1374. doi: 10.1016/s0140-6736(74)92233-8. [DOI] [PubMed] [Google Scholar]
  2. Blake P. A., Allegra D. T., Snyder J. D., Barrett T. J., McFarland L., Caraway C. T., Feeley J. C., Craig J. P., Lee J. V., Puhr N. D. Cholera--a possible endemic focus in the United States. N Engl J Med. 1980 Feb 7;302(6):305–309. doi: 10.1056/NEJM198002073020601. [DOI] [PubMed] [Google Scholar]
  3. Blake P. A. Epidemiology of cholera in the Americas. Gastroenterol Clin North Am. 1993 Sep;22(3):639–660. [PubMed] [Google Scholar]
  4. Blake P. A., Rosenberg M. L., Florencia J., Costa J. B., do Prado Quintino L., Gangarosa E. J. Cholera in Portugal, 1974. II. Transmission by bottled mineral water. Am J Epidemiol. 1977 Apr;105(4):344–348. doi: 10.1093/oxfordjournals.aje.a112392. [DOI] [PubMed] [Google Scholar]
  5. Centers for Disease Control (CDC) Update: cholera--Western Hemisphere, 1991. MMWR Morb Mortal Wkly Rep. 1991 Dec 13;40(49):860–860. [PubMed] [Google Scholar]
  6. Centers for Disease Control and Prevention (CDC) Surveillance for cholera--Cochabamba Department, Bolivia, January-June 1992. MMWR Morb Mortal Wkly Rep. 1993 Aug 27;42(33):636–639. [PubMed] [Google Scholar]
  7. Cárdenas V., Saad C., Varona M., Linero M. Waterborne cholera in Riohacha, Colombia, 1992. Bull Pan Am Health Organ. 1993;27(4):313–330. [PubMed] [Google Scholar]
  8. Feachem R. G. Interventions for the control of diarrhoeal diseases among young children: promotion of personal and domestic hygiene. Bull World Health Organ. 1984;62(3):467–476. [PMC free article] [PubMed] [Google Scholar]
  9. Finelli L., Swerdlow D., Mertz K., Ragazzoni H., Spitalny K. Outbreak of cholera associated with crab brought from an area with epidemic disease. J Infect Dis. 1992 Dec;166(6):1433–1435. doi: 10.1093/infdis/166.6.1433. [DOI] [PubMed] [Google Scholar]
  10. Kirchhoff L. V., McClelland K. E., Do Carmo Pinho M., Araujo J. G., De Sousa M. A., Guerrant R. L. Feasibility and efficacy of in-home water chlorination in rural North-eastern Brazil. J Hyg (Lond) 1985 Apr;94(2):173–180. doi: 10.1017/s0022172400061374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kolvin J. L., Roberts D. Studies on the growth of Vibrio cholerae biotype eltor and biotype classical in foods. J Hyg (Lond) 1982 Oct;89(2):243–252. doi: 10.1017/s0022172400070777. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Lowry P. W., Pavia A. T., McFarland L. M., Peltier B. H., Barrett T. J., Bradford H. B., Quan J. M., Lynch J., Mathison J. B., Gunn R. A. Cholera in Louisiana. Widening spectrum of seafood vehicles. Arch Intern Med. 1989 Sep;149(9):2079–2084. doi: 10.1001/archinte.149.9.2079. [DOI] [PubMed] [Google Scholar]
  13. McIntyre R. C., Tira T., Flood T., Blake P. A. Modes of transmission of cholera in a newly infected population on an atoll: implications for control measures. Lancet. 1979 Feb 10;1(8111):311–314. doi: 10.1016/s0140-6736(79)90719-0. [DOI] [PubMed] [Google Scholar]
  14. Merson M. H., Martin W. T., Craig J. P., Morris G. K., Blake P. A., Craun G. F., Feeley J. C., Camacho J. C., Gangarosa E. J. Cholera on Guam, 1974: epidemiologic findings and isolation of non-toxinogenic strains. Am J Epidemiol. 1977 Apr;105(4):349–361. doi: 10.1093/oxfordjournals.aje.a112393. [DOI] [PubMed] [Google Scholar]
  15. Mujica O. J., Quick R. E., Palacios A. M., Beingolea L., Vargas R., Moreno D., Barrett T. J., Bean N. H., Seminario L., Tauxe R. V. Epidemic cholera in the Amazon: the role of produce in disease risk and prevention. J Infect Dis. 1994 Jun;169(6):1381–1384. doi: 10.1093/infdis/169.6.1381. [DOI] [PubMed] [Google Scholar]
  16. Ries A. A., Vugia D. J., Beingolea L., Palacios A. M., Vasquez E., Wells J. G., Garcia Baca N., Swerdlow D. L., Pollack M., Bean N. H. Cholera in Piura, Peru: a modern urban epidemic. J Infect Dis. 1992 Dec;166(6):1429–1433. doi: 10.1093/infdis/166.6.1429. [DOI] [PubMed] [Google Scholar]
  17. Swerdlow D. L., Mintz E. D., Rodriguez M., Tejada E., Ocampo C., Espejo L., Greene K. D., Saldana W., Seminario L., Tauxe R. V. Waterborne transmission of epidemic cholera in Trujillo, Peru: lessons for a continent at risk. Lancet. 1992 Jul 4;340(8810):28–33. doi: 10.1016/0140-6736(92)92432-f. [DOI] [PubMed] [Google Scholar]
  18. Tamplin M. L., Carrillo Parodi C. Environmental spread of Vibrio cholerae in Peru. Lancet. 1991 Nov 9;338(8776):1216–1217. doi: 10.1016/0140-6736(91)92089-k. [DOI] [PubMed] [Google Scholar]
  19. Weber J. T., Mintz E. D., Cañizares R., Semiglia A., Gomez I., Sempértegui R., Dávila A., Greene K. D., Puhr N. D., Cameron D. N. Epidemic cholera in Ecuador: multidrug-resistance and transmission by water and seafood. Epidemiol Infect. 1994 Feb;112(1):1–11. doi: 10.1017/s0950268800057368. [DOI] [PMC free article] [PubMed] [Google Scholar]

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