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. 1995 Apr;114(2):385–391. doi: 10.1017/s0950268800058015

Prevalence of human astrovirus serotype 4: capsid protein sequence and comparison with other strains.

M M Willcocks 1, J B Kurtz 1, T W Lee 1, M J Carter 1
PMCID: PMC2271283  PMID: 7705498

Abstract

Astrovirus serotype 4 has increased in relative prevalence in the Oxford, UK area in 1993. The structural gene of human astrovirus serotype 4 has been sequenced and the results indicate that this protein differs substantially from serotypes 1 and 2. In particular, conservation at the C terminus is greatly reduced. However, amino acid substitutions in this region show a strong conservation in character suggesting that structural or functional constraints operate in this region.

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Selected References

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