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. 1995 Feb;114(1):161–168. doi: 10.1017/s0950268800052018

DNA typing of epidemiologically-related isolates of Aspergillus fumigatus.

M Birch 1, N Nolard 1, G S Shankland 1, D W Denning 1
PMCID: PMC2271353  PMID: 7867735

Abstract

Invasive aspergillosis is often nosocomially acquired and carries a high mortality. Molecular typing methods to discriminate isolates have now been developed. Using simple restriction endonuclease (Sal1 and Xho1) digestion of total genomic DNA, we have typed 25 epidemiologically-related isolates of A. fumigatus from six hospital episodes of invasive aspergillosis. Eight DNA types were found and in each case the DNA type matched precisely the epidemiological data. Thus DNA typing of A. fumigatus can provide the means to match isolates from linked sources and distinguish isolates from diverse origins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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