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. 1993 Oct;111(2):245–255. doi: 10.1017/s0950268800056958

Epidemiological investigation of risk factors for campylobacter colonization in Norwegian broiler flocks.

G Kapperud 1, E Skjerve 1, L Vik 1, K Hauge 1, A Lysaker 1, I Aalmen 1, S M Ostroff 1, M Potter 1
PMCID: PMC2271384  PMID: 8405152

Abstract

An epidemiological investigation was conducted to identify risk factors related to hygiene and husbandry practices which determine the introduction of Campylobacter spp. into broiler chicken flocks. All 176 broiler farms in an area in southeastern Norway participated in the study. Each farm was represented by one flock selected at random during a one-year period. The flocks were examined for campylobacter colonization at slaughter, and the flock managers were subsequently interviewed about hygiene and husbandry practices. Campylobacter spp. were recovered from 32 (18%) of the flocks. The proportion of colonized flocks varied geographically and seasonally with a peak in the autumn. The following variables were found to be independently associated with an increased risk of campylobacter colonization using logistic regression analysis: (i) feeding the broilers undisinfected water (odds ratio (OR) = 3.42, P = 0.045), (ii) tending other poultry prior to entering the broiler house (OR = 6.43, P = 0.007), (iii) tending pigs before entering the house (OR = 4.86, P = 0.037), (iv) geographic region (Hedmark versus Ostfold county) (OR = 2.91, P = 0.023, (v) season (autumn versus other seasons) (OR = 3.43; P = 0.008). Presence of rats on the farm was associated with an increased risk, but this factor did not reach statistical significance (OR = 3.96, P = 0.083). Preventive measures should include disinfection of drinking water and strict hygienic routines when the farm workers enter the rearing room. The results indicate that disinfection of drinking water is the preventive measure most likely to have the greatest impact on the prevalence of campylobacter among broiler chicken flocks in the study area (population attributable fraction = 0.53).

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Selected References

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  1. Annan-Prah A., Janc M. The mode of spread of Campylobacter jejuni/coli to broiler flocks. Zentralbl Veterinarmed B. 1988 Jan;35(1):11–18. doi: 10.1111/j.1439-0450.1988.tb00461.x. [DOI] [PubMed] [Google Scholar]
  2. Blaser M. J., Taylor D. N., Feldman R. A. Epidemiology of Campylobacter jejuni infections. Epidemiol Rev. 1983;5:157–176. doi: 10.1093/oxfordjournals.epirev.a036256. [DOI] [PubMed] [Google Scholar]
  3. Brennhovd O., Kapperud G., Langeland G. Survey of thermotolerant Campylobacter spp. and Yersinia spp. in three surface water sources in Norway. Int J Food Microbiol. 1992 Mar-Apr;15(3-4):327–338. doi: 10.1016/0168-1605(92)90066-c. [DOI] [PubMed] [Google Scholar]
  4. Butzler J. P., Skirrow M. B. Campylobacter enteritis. Clin Gastroenterol. 1979 Sep;8(3):737–765. [PubMed] [Google Scholar]
  5. Deming M. S., Tauxe R. V., Blake P. A., Dixon S. E., Fowler B. S., Jones T. S., Lockamy E. A., Patton C. M., Sikes R. O. Campylobacter enteritis at a university: transmission from eating chicken and from cats. Am J Epidemiol. 1987 Sep;126(3):526–534. doi: 10.1093/oxfordjournals.aje.a114685. [DOI] [PubMed] [Google Scholar]
  6. Harris N. V., Thompson D., Martin D. C., Nolan C. M. A survey of Campylobacter and other bacterial contaminants of pre-market chicken and retail poultry and meats, King County, Washington. Am J Public Health. 1986 Apr;76(4):401–406. doi: 10.2105/ajph.76.4.401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hopkins R. S., Olmsted R., Istre G. R. Endemic Campylobacter jejuni infection in Colorado: identified risk factors. Am J Public Health. 1984 Mar;74(3):249–250. doi: 10.2105/ajph.74.3.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Izat A. L., Gardner F. A. Incidence of Campylobacter jejuni in processed egg products. Poult Sci. 1988 Oct;67(10):1431–1435. doi: 10.3382/ps.0671431. [DOI] [PubMed] [Google Scholar]
  9. Kapperud G., Aasen S. Descriptive epidemiology of infections due to thermotolerant Campylobacter spp. in Norway, 1979-1988. APMIS. 1992 Oct;100(10):883–890. [PubMed] [Google Scholar]
  10. Kapperud G., Lassen J., Ostroff S. M., Aasen S. Clinical features of sporadic Campylobacter infections in Norway. Scand J Infect Dis. 1992;24(6):741–749. doi: 10.3109/00365549209062459. [DOI] [PubMed] [Google Scholar]
  11. Kapperud G., Skjerve E., Bean N. H., Ostroff S. M., Lassen J. Risk factors for sporadic Campylobacter infections: results of a case-control study in southeastern Norway. J Clin Microbiol. 1992 Dec;30(12):3117–3121. doi: 10.1128/jcm.30.12.3117-3121.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Kazwala R. R., Collins J. D., Hannan J., Crinion R. A., O'Mahony H. Factors responsible for the introduction and spread of Campylobacter jejuni infection in commercial poultry production. Vet Rec. 1990 Mar 31;126(13):305–306. [PubMed] [Google Scholar]
  13. Lindblom G. B., Sjörgren E., Kaijser B. Natural campylobacter colonization in chickens raised under different environmental conditions. J Hyg (Lond) 1986 Jun;96(3):385–391. doi: 10.1017/s0022172400066146. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Myszewski M. A., Stern N. J. Influence of Campylobacter jejuni cecal colonization on immunoglobulin response in chickens. Avian Dis. 1990 Jul-Sep;34(3):588–594. [PubMed] [Google Scholar]
  15. Norkrans G., Svedhem A. Epidemiological aspects of Campylobacter jejuni enteritis. J Hyg (Lond) 1982 Aug;89(1):163–170. doi: 10.1017/s0022172400070662. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Oosterom J., den Uyl C. H., Bänffer J. R., Huisman J. Epidemiological investigations on Campylobacter jejuni in households with a primary infection. J Hyg (Lond) 1984 Oct;93(2):325–332. doi: 10.1017/s002217240006486x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Pearson A. D., Greenwood M., Healing T. D., Rollins D., Shahamat M., Donaldson J., Colwell R. R. Colonization of broiler chickens by waterborne Campylobacter jejuni. Appl Environ Microbiol. 1993 Apr;59(4):987–996. doi: 10.1128/aem.59.4.987-996.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Rollins D. M., Colwell R. R. Viable but nonculturable stage of Campylobacter jejuni and its role in survival in the natural aquatic environment. Appl Environ Microbiol. 1986 Sep;52(3):531–538. doi: 10.1128/aem.52.3.531-538.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Rosef O., Gondrosen B., Kapperud G., Underdal B. Isolation and characterization of Campylobacter jejuni and Campylobacter coli from domestic and wild mammals in Norway. Appl Environ Microbiol. 1983 Oct;46(4):855–859. doi: 10.1128/aem.46.4.855-859.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Schoeni J. L., Doyle M. P. Reduction of Campylobacter jejuni colonization of chicks by cecum-colonizing bacteria producing anti-C. jejuni metabolites. Appl Environ Microbiol. 1992 Feb;58(2):664–670. doi: 10.1128/aem.58.2.664-670.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Shanker S., Lee A., Sorrell T. C. Campylobacter jejuni in broilers: the role of vertical transmission. J Hyg (Lond) 1986 Apr;96(2):153–159. doi: 10.1017/s002217240006592x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Shanker S., Lee A., Sorrell T. C. Horizontal transmission of Campylobacter jejuni amongst broiler chicks: experimental studies. Epidemiol Infect. 1990 Feb;104(1):101–110. doi: 10.1017/s0950268800054571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Sjögren E., Kaijser B. Serotyping studies of Campylobacter from naturally colonized chickens. Epidemiol Infect. 1989 Apr;102(2):215–219. doi: 10.1017/s0950268800029885. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Skirrow M. B., Benjamin J. Differentiation of enteropathogenic Campylobacter. J Clin Pathol. 1980 Nov;33(11):1122–1122. doi: 10.1136/jcp.33.11.1122. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Stern N. J., Bailey J. S., Blankenship L. C., Cox N. A., McHan F. Colonization characteristics of Campylobacter jejuni in chick ceca. Avian Dis. 1988 Apr-Jun;32(2):330–334. [PubMed] [Google Scholar]
  26. Stern N. J., Meinersmann R. J., Cox N. A., Bailey J. S., Blankenship L. C. Influence of host lineage on cecal colonization by Campylobacter jejuni in chickens. Avian Dis. 1990 Jul-Sep;34(3):602–606. [PubMed] [Google Scholar]
  27. Stern N. J., Meinersmann R. J., Dickerson H. W. Influence of antibody treatment of Campylobacter jejuni on the dose required to colonize chicks. Avian Dis. 1990 Jul-Sep;34(3):595–601. [PubMed] [Google Scholar]
  28. van de Giessen A., Mazurier S. I., Jacobs-Reitsma W., Jansen W., Berkers P., Ritmeester W., Wernars K. Study on the epidemiology and control of Campylobacter jejuni in poultry broiler flocks. Appl Environ Microbiol. 1992 Jun;58(6):1913–1917. doi: 10.1128/aem.58.6.1913-1917.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]

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