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. 1994 Apr;112(2):307–314. doi: 10.1017/s0950268800057721

Cell surface hydrophobicity and adherence to extra-cellular matrix proteins in two collections of methicillin-resistant Staphylococcus aureus.

R G Cree 1, P Aleljung 1, M Paulsson 1, W Witte 1, W C Noble 1, A Ljungh 1, T Wadström 1
PMCID: PMC2271452  PMID: 8150005

Abstract

Non-specific and specific mechanisms of adherence have been examined in two collections of methicillin-resistant Staphylococcus aureus (MRSA). Determination of hydrophobicity by salt aggregation, hydrophobicity indices and of adherence to the extra-cellular matrix proteins fibronectin, vitronectin, laminin and collagen type 1 have failed to reveal any correlation with phage-type, plasmid profile or antibiogram. Further, the strain collections, made over a period of years in two countries, differ markedly in their adherence characteristics; MRSA are heterogeneous in this respect. Such heterogeneity may explain the polarization of views on the epidemicity or 'virulence' of MRSA. With the exception of adherence to collagen a small group of methicillin sensitive S. aureus had characteristics intermediate between the two groups of MRSA.

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Selected References

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