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. 1996 Aug;117(1):149–157. doi: 10.1017/s0950268800001254

Outbreak of vertigo in Wyoming: possible role of an enterovirus infection.

L Simonsen 1, A S Khan 1, H E Gary Jr 1, C Hanson 1, M A Pallansch 1, S Music 1, R C Holman 1, J A Stewart 1, D D Erdman 1, N H Arden 1, I K Arenberg 1, L B Schonberger 1
PMCID: PMC2271687  PMID: 8760963

Abstract

An epidemiologic investigation was conducted to characterize and evaluate the possibility of a viral aetiology of an outbreak of acute vertigo in Hot Springs Country, Wyoming, during autumn 1992. Case-finding identified Hot Springs County residents who sought medical attention for new onset vertigo during 1 August, 1992-31 January 1993. Thirty-five case-patients and 61 matched controls were interviewed and serum specimens were obtained during January 1993. Case-patients were more likely than controls to report symptoms (e.g. fatigue, sore throat, fever, diarrhoea) of antecedent acute illness. Case-patients did not have a significantly greater prevalence or mean titre of IgG antibodies to respiratory syncytial virus, parainfluenza viruses, Epstein-Barr virus, and cytomegalovirus than controls. Serologic evidence of recent enterovirus infection (IgM antibodies) was found for 74% of case-patients compared with 54% of controls (P < 0.05), suggesting a possible association between vertigo and enterovirus infection. Future studies are needed to define the role of enteroviruses in innerear diseases.

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Selected References

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