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. 1990 Apr;104(2):171–180. doi: 10.1017/s0950268800059331

Phenotypic variation amongst genotypically homogeneous Legionella pneumophila serogroup 1 isolates: implications for the investigation of outbreaks of Legionnaires' disease.

T G Harrison 1, N A Saunders 1, A Haththotuwa 1, G Hallas 1, R J Birtles 1, A G Taylor 1
PMCID: PMC2271750  PMID: 1969803

Abstract

One hundred and seventy-nine isolates of Legionella pneumophila serogroup 1, obtained from a site associated with an outbreak of Legionnaires' disease, were examined by monoclonal antibody subgrouping, restriction fragment length polymorphism typing, restriction endonuclease analysis and plasmid content. Nine distinct phenotypes were detected but at the genotypic level all strains were closely related. The data presented indicate that phenotypic variation of a single parent strain can occur within an environmental site. The implications of these findings are discussed in relation to the investigation of outbreaks of Legionnaires' disease.

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Selected References

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