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. 1990 Aug;105(1):59–64. doi: 10.1017/s0950268800047646

Plasmid profile analysis and antimicrobial susceptibility patterns of Shigella isolates from Nigeria.

D K Olukoya 1, O Oni 1
PMCID: PMC2271807  PMID: 2200702

Abstract

In an epidemiological survey, plasmid profiles and antimicrobial susceptibility testing of 100 shigella isolates in Lagos, Nigeria was done. All the isolates were sensitive to nalidixic acid, nitrofurantoin and ciprofloxacin. The commonest antimicrobial susceptibility pattern was resistance to ampicillin, colistin sulphate, co-trimoxazole, streptomycin and tetracycline. All but 4 of 100 isolates screened contained one or more plasmids. Plasmid profile analysis distinguished more strains than did antimicrobial susceptibility patterns. A total of 36 isolates was able to transfer resistance plasmids to Escherichia coli K-12 by conjugation. Using in vitro transformation, seven isolates transferred resistance. These plasmids specified resistance to tetracycline, streptomycin, sulphonamide, trimethoprim and ampicillin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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