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. 1991 Aug;107(1):81–86. doi: 10.1017/s0950268800048706

A large outbreak of gastroenteritis associated with a small round structured virus among schoolchildren and teachers in Japan.

S Kobayashi 1, T Morishita 1, T Yamashita 1, K Sakae 1, O Nishio 1, T Miyake 1, Y Ishihara 1, S Isomura 1
PMCID: PMC2272036  PMID: 1879493

Abstract

In March 1989 a large outbreak of acute gastroenteritis occurred simultaneously among schoolchildren and teachers at nine elementary schools in Toyota City, Japan. Illness was observed in 3236 (41.5%) of 7801 schoolchildren and 117 (39.4%) of 297 teachers. The main clinical symptoms were diarrhoea, vomiting, nausea and abdominal pain. Gastroenteritis was significantly associated with the consumption of school lunch served by one particular lunch preparation centre. One food handler at the centre suffered from gastroenteritis during the outbreak. Small round structured virus (SRSV) was detected in 4 of 8 stool specimens from sick persons. The school lunch contaminated by the infected food handler is the most probable source of this outbreak due to SRSV.

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Selected References

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  1. Adler J. L., Zickl R. Winter vomiting disease. J Infect Dis. 1969 Jun;119(6):668–673. doi: 10.1093/infdis/119.6.668. [DOI] [PubMed] [Google Scholar]
  2. Brondum J., Spitalny K. C., Vogt R. L., Godlewski K., Madore H. P., Dolin R. Snow Mountain agent associated with an outbreak of gastroenteritis in Vermont. J Infect Dis. 1985 Oct;152(4):834–837. doi: 10.1093/infdis/152.4.834. [DOI] [PubMed] [Google Scholar]
  3. Dolin R., Blacklow N. R., DuPont H., Buscho R. F., Wyatt R. G., Kasel J. A., Hornick R., Chanock R. M. Biological properties of Norwalk agent of acute infectious nonbacterial gastroenteritis. Proc Soc Exp Biol Med. 1972 Jun;140(2):578–583. doi: 10.3181/00379727-140-36508. [DOI] [PubMed] [Google Scholar]
  4. Dolin R., Reichman R. C., Roessner K. D., Tralka T. S., Schooley R. T., Gary W., Morens D. Detection by immune electron microscopy of the Snow Mountain agent of acute viral gastroenteritis. J Infect Dis. 1982 Aug;146(2):184–189. doi: 10.1093/infdis/146.2.184. [DOI] [PubMed] [Google Scholar]
  5. Dolin R., Treanor J. J., Madore H. P. Novel agents of viral enteritis in humans. J Infect Dis. 1987 Mar;155(3):365–376. doi: 10.1093/infdis/155.3.365. [DOI] [PubMed] [Google Scholar]
  6. Flewett T. H., Bryden A. S., Davies H. Diagnostic electron microscopy of faeces. I. The viral flora of the faeces as seen by electron microscopy. J Clin Pathol. 1974 Aug;27(8):603–608. doi: 10.1136/jcp.27.8.603. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gill O. N., Cubitt W. D., McSwiggan D. A., Watney B. M., Bartlett C. L. Epidemic of gastroenteritis caused by oysters contaminated with small round structured viruses. Br Med J (Clin Res Ed) 1983 Nov 19;287(6404):1532–1534. doi: 10.1136/bmj.287.6404.1532. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Heun E. M., Vogt R. L., Hudson P. J., Parren S., Gary G. W. Risk factors for secondary transmission in households after a common-source outbreak of Norwalk gastroenteritis. Am J Epidemiol. 1987 Dec;126(6):1181–1186. doi: 10.1093/oxfordjournals.aje.a114756. [DOI] [PubMed] [Google Scholar]
  9. Kapikian A. Z., Wyatt R. G., Dolin R., Thornhill T. S., Kalica A. R., Chanock R. M. Visualization by immune electron microscopy of a 27-nm particle associated with acute infectious nonbacterial gastroenteritis. J Virol. 1972 Nov;10(5):1075–1081. doi: 10.1128/jvi.10.5.1075-1081.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kaplan J. E., Feldman R., Campbell D. S., Lookabaugh C., Gary G. W. The frequency of a Norwalk-like pattern of illness in outbreaks of acute gastroenteritis. Am J Public Health. 1982 Dec;72(12):1329–1332. doi: 10.2105/ajph.72.12.1329. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kaplan J. E., Gary G. W., Baron R. C., Singh N., Schonberger L. B., Feldman R., Greenberg H. B. Epidemiology of Norwalk gastroenteritis and the role of Norwalk virus in outbreaks of acute nonbacterial gastroenteritis. Ann Intern Med. 1982 Jun;96(6 Pt 1):756–761. doi: 10.7326/0003-4819-96-6-756. [DOI] [PubMed] [Google Scholar]
  12. Kuritsky J. N., Osterholm M. T., Greenberg H. B., Korlath J. A., Godes J. R., Hedberg C. W., Forfang J. C., Kapikian A. Z., McCullough J. C., White K. E. Norwalk gastroenteritis: a community outbreak associated with bakery product consumption. Ann Intern Med. 1984 Apr;100(4):519–521. doi: 10.7326/0003-4819-100-4-519. [DOI] [PubMed] [Google Scholar]
  13. Kuritsky J. N., Osterholm M. T., Korlath J. A., White K. E., Kaplan J. E. A statewide assessment of the role of Norwalk virus in outbreaks of food-borne gastroenteritis. J Infect Dis. 1985 Mar;151(3):568–568. doi: 10.1093/infdis/151.3.568. [DOI] [PubMed] [Google Scholar]
  14. Morse D. L., Guzewich J. J., Hanrahan J. P., Stricof R., Shayegani M., Deibel R., Grabau J. C., Nowak N. A., Herrmann J. E., Cukor G. Widespread outbreaks of clam- and oyster-associated gastroenteritis. Role of Norwalk virus. N Engl J Med. 1986 Mar 13;314(11):678–681. doi: 10.1056/NEJM198603133141103. [DOI] [PubMed] [Google Scholar]
  15. Murphy A. M., Grohmann G. S., Christopher P. J., Lopez W. A., Davey G. R., Millsom R. H. An Australia-wide outbreak of gastroenteritis from oysters caused by Norwalk virus. Med J Aust. 1979 Oct 6;2(7):329–333. doi: 10.5694/j.1326-5377.1979.tb104133.x. [DOI] [PubMed] [Google Scholar]
  16. Nishio O., Ishihara Y., Isomura S., Inoue H., Inouye S. Long-term follow-up of infants from birth for rotavirus antigen and antibody in the feces. Acta Paediatr Jpn. 1988 Aug;30(4):497–504. doi: 10.1111/j.1442-200x.1988.tb02542.x. [DOI] [PubMed] [Google Scholar]
  17. Riordan T., Craske J., Roberts J. L., Curry A. Food borne infection by a Norwalk like virus (small round structured virus). J Clin Pathol. 1984 Jul;37(7):817–820. doi: 10.1136/jcp.37.7.817. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Schreiber D. S., Blacklow N. R., Trier J. S. The small intestinal lesion induced by Hawaii agent acute infectious nonbacterial gastroenteritis. J Infect Dis. 1974 Jun;129(6):705–708. doi: 10.1093/infdis/129.6.705. [DOI] [PubMed] [Google Scholar]
  19. Taniguchi K., Urasawa S., Urasawa T. Virus-like particle, 35 to 40 nm, associated with an institutional outbreak of acute gastroenteritis in adults. J Clin Microbiol. 1979 Nov;10(5):730–736. doi: 10.1128/jcm.10.5.730-736.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Thornhill T. S., Kalica A. R., Wyatt R. G., Kapikian A. Z., Chanock R. M. Pattern of shedding of the Norwalk particle in stools during experimentally induced gastroenteritis in volunteers as determined by immune electron microscopy. J Infect Dis. 1975 Jul;132(1):28–34. doi: 10.1093/infdis/132.1.28. [DOI] [PubMed] [Google Scholar]
  21. White K. E., Osterholm M. T., Mariotti J. A., Korlath J. A., Lawrence D. H., Ristinen T. L., Greenberg H. B. A foodborne outbreak of Norwalk virus gastroenteritis. Evidence for post-recovery transmission. Am J Epidemiol. 1986 Jul;124(1):120–126. doi: 10.1093/oxfordjournals.aje.a114356. [DOI] [PubMed] [Google Scholar]

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