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Epidemiology and Infection logoLink to Epidemiology and Infection
. 1991 Dec;107(3):685–691. doi: 10.1017/s0950268800049384

High prevalence rates of antibody to three sandfly fever viruses (Sicilian, Naples, and Toscana) among Cypriots.

R Eitrem 1, M Stylianou 1, B Niklasson 1
PMCID: PMC2272099  PMID: 1661242

Abstract

Neutralizing antibodies to sandfly fever Naples, sandfly fever Sicilian and Toscana viruses were investigated among 479 sera collected from a normal human population in Cyprus. Antibody prevalence rates of 57%, 32% and 20% were found to Naples, Sicilian and Toscana viruses, respectively. The observed frequency of dual and triple infections was higher than would be expected with a random chance of infection. Antibody prevalence rates were similar for men and women for all three viruses tested, but one of two study sites had significantly higher antibody prevalence to Naples and Sicilian viruses than the other. Individuals with antibodies to both Naples and Toscana viruses had higher antibody levels to Naples virus than those with antibodies to Naples virus only. If the antibody prevalence rates found in this study reflect a history of clinical disease as described in the literature, sandfly fever poses a significant public health problem in Cyprus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Earley E., Peralta P. H., Johnson K. M. A plaque neutralization method for arboviruses. Proc Soc Exp Biol Med. 1967 Jul;125(3):741–747. doi: 10.3181/00379727-125-32194. [DOI] [PubMed] [Google Scholar]
  2. Ehrnst A., Peters C. J., Niklasson B., Svedmyr A., Holmgren B. Neurovirulent Toscana virus (a sandfly fever virus) in Swedish man after visit to Portugal. Lancet. 1985 May 25;1(8439):1212–1213. doi: 10.1016/s0140-6736(85)92886-7. [DOI] [PubMed] [Google Scholar]
  3. Eitrem R., Niklasson B., Weiland O. Sandfly fever among Swedish tourists. Scand J Infect Dis. 1991;23(4):451–457. doi: 10.3109/00365549109075093. [DOI] [PubMed] [Google Scholar]
  4. Eitrem R., Vene S., Niklasson B. Incidence of sand fly fever among Swedish United Nations soldiers on Cyprus during 1985. Am J Trop Med Hyg. 1990 Aug;43(2):207–211. doi: 10.4269/ajtmh.1990.43.207. [DOI] [PubMed] [Google Scholar]
  5. McCown J. M., Brandt W. E., Bancroft W. H., Russell P. K. Dimethyl sulfoxide enhancement of phlebotomus fever virus plaque formation. Am J Trop Med Hyg. 1979 Jul;28(4):733–739. [PubMed] [Google Scholar]
  6. Niklasson B., Eitrem R. Sandfly fever among Swedish UN troops in Cyprus. Lancet. 1985 May 25;1(8439):1212–1212. doi: 10.1016/s0140-6736(85)92885-5. [DOI] [PubMed] [Google Scholar]
  7. Tesh R. B., Duboise S. M. Viremia and immune response with sequential phlebovirus infections. Am J Trop Med Hyg. 1987 May;36(3):662–668. doi: 10.4269/ajtmh.1987.36.662. [DOI] [PubMed] [Google Scholar]
  8. Tesh R. B., Saidi S., Gajdamovic S. J., Rodhain F., Vesenjak-Hirjan J. Serological studies on the epidemiology of sandfly fever in the Old World. Bull World Health Organ. 1976;54(6):663–674. [PMC free article] [PubMed] [Google Scholar]
  9. Verani P., Ciufolini M. G., Caciolli S., Renzi A., Nicoletti L., Sabatinelli G., Bartolozzi D., Volpi G., Amaducci L., Coluzzi M. Ecology of viruses isolated from sand flies in Italy and characterized of a new Phlebovirus (Arabia virus). Am J Trop Med Hyg. 1988 Mar;38(2):433–439. doi: 10.4269/ajtmh.1988.38.433. [DOI] [PubMed] [Google Scholar]
  10. Verani P., Nicoletti L., Ciufolini M. G. Antigenic and biological characterization of Toscana virus, a new Phlebotomus fever group virus isolated in Italy. Acta Virol. 1984 Jan;28(1):39–47. [PubMed] [Google Scholar]

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