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Mean intracerebral 9L tumor doubling times (± SE) before BCNU administration (Tdpre; empty bars) and during the exponential regrowth phase (Tdpost; filled bars) after BCNU treatment. Statistically significant differences found before and after BCNU treatment (P < 0.03) using a two-tailed paired Student’s t test are indicated (∗). In addition, differences between Tdpost for each posttreatment group were found to be statistically significant (P < 0.05).
