Skip to main content
Canadian Family Physician logoLink to Canadian Family Physician
. 1975 May;21(5):107, 109, 111.

Spectinomycin Hydrochloride (Trobicin) in the Treatment of Gonorrhea

W T R Linton, B Hamilton-Smith, R L Persad
PMCID: PMC2274604  PMID: 20469188

Abstract

A clinical trial of spectinomycin (Trobicin) in acute gonorrhea in men was conducted in the Special Treatment Clinic at St. Michael's Hospital, Toronto, between August 1970 and February 1972. One hundred and forty men with clinical symptoms of gonorrhea received 2 g spectinomycin HC1 in a single dose intramuscularly. Of these, 101 returned seven days later for reassessment. Of these, 84 had a complete follow-up, with a bacteriological cure rate of 95 percent and a clinical cure rate of 91.8 percent. Therefore we conclude that spectinomycin HC1 (Trobicin; Upjohn) is a useful drug for the treatment of acute gonorrhea in males.

Full text

PDF
107

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CLARK J. W., Jr, YOBS A. R. EFFECT OF ACTINOSPECTACIN IN EXPERIMENTAL SYPHILIS IN THE RABBIT. I. EARLY LESION SYPHILIS. Br J Vener Dis. 1963 Sep;39:184–189. doi: 10.1136/sti.39.3.184. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hafermann D. R., Cooper T. S., Chesney M. A. Spectinomycin for Asian-acquired gonorrhea. Mil Med. 1973 Jan;138(1):14–15. [PubMed] [Google Scholar]
  3. Sim S. K. Chemotherapy of gonorrhea: a review of current status. Can Med Assoc J. 1972 Nov 18;107(10):986–992. [PMC free article] [PubMed] [Google Scholar]
  4. WILLCOX R. R. Trobicin (actinospectacin) in non-gonococcal urethritis. Br J Vener Dis. 1963 Mar;39:21–23. doi: 10.1136/sti.39.1.21. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. WILLCOX R. R. Trobicin (actinospectacin), a new injectable antibiotic in the treatment of gonorrhoea. Br J Vener Dis. 1962 Sep;38:150–153. doi: 10.1136/sti.38.3.150. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Willcox R. R. Spectinomycin in the treatment of gonorrhoea in males. Br J Vener Dis. 1974 Aug;50(4):294–297. doi: 10.1136/sti.50.4.294. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Canadian Family Physician are provided here courtesy of College of Family Physicians of Canada

RESOURCES