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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Biomaterials. 2008 Mar;29(8):994–1004. doi: 10.1016/j.biomaterials.2007.10.042

Table 2.

Nuclear bag fiber differentiation by Neuregulin 1-β-1 EGF treatment.

Surface Nrg1-β-1
(ng/ml)
# of Bag Fibers # of Myotubes Intrafusal fiber
Differentiation Index
DETA 0.00 6.00±0.32 306.17 0.0196
DETA 10.00 6.00±44 333.33 0.0209
DETA 20.00 7.66±0.38 330.33 0.0233
DETA 100.00 30.83±0.69 310.17 0.1002
Collagen 0.00 6.13±0.53 325.00 0.0189
Collagen 100.00 32.67±1.53 325.00 0.1005

The number of bag fibers and the number of myotubes are averages of ten experiments all performed in triplicate. Data is reported as the mean ± the standard error of the mean. The differentiation index is the ratio of observed bag fibers to total myotubes with greater than four nuclei.