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Canadian Family Physician logoLink to Canadian Family Physician
. 1998 Mar;44:495, 497-498.

Motherisk Update

Lori Shapiro, Anne Pastuszak, Giancarla Curto, Gideon Koren
PMCID: PMC2277705  PMID: 9559187

Abstract

QUESTION

One of my patients conceived while using a topical tretinoin preparation for acne. I know this drug is related to Accutane, which is teratogenic. How should I advise her?

ANSWER

Available evidence suggests that topical tretinoin does not increase teratogenic risk in humans.

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