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. 1995 Jan;33(1):1–7. doi: 10.1128/jcm.33.1.1-7.1995

Bordetella holmesii sp. nov., a new gram-negative species associated with septicemia.

R S Weyant 1, D G Hollis 1, R E Weaver 1, M F Amin 1, A G Steigerwalt 1, S P O'Connor 1, A M Whitney 1, M I Daneshvar 1, C W Moss 1, D J Brenner 1
PMCID: PMC227868  PMID: 7699023

Abstract

CDC nonoxidizer group 2 (NO-2) currently consists of 15 gram-negative, rod-shaped, oxidase-negative, asaccharolytic, brown soluble pigment-producing strains isolated from blood cultures, usually from young adults. On the basis of their cellular fatty acid profiles, NO-2 strains formed a single group that was identical with the profile of Bordetella avium. 16S rRNA sequencing of one NO-2 strain and the type strains of B. pertussis, B. parapertussis, B. bronchiseptica, and B. avium showed a high degree of homology (> or = 98% over 1,525 bases). The NO-2 guanine-plus-cytosine content (61.5 to 62.3 mol%) and major ubiquinone analysis (ubiquinone-8) results were both consistent with those for the genus Bordetella. DNA relatedness studies (hydroxyapatite method) confirmed a close relatedness between NO-2 and Bordetella species and demonstrated that NO-2 strains were a single new species. The name B. holmesii sp. nov. is proposed for CDC group NO-2.

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Selected References

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