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. 1995 Feb;33(2):484–486. doi: 10.1128/jcm.33.2.484-486.1995

Diagnostic value of detecting JC virus DNA in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy.

I W Fong 1, C B Britton 1, K E Luinstra 1, E Toma 1, J B Mahony 1
PMCID: PMC227972  PMID: 7714213

Abstract

JC virus DNA was detected by PCR in the cerebrospinal fluid of 17 of 23 (73.9%) patients with confirmed cases of progressive multifocal leukoencephalopathy and 2 of 48 (4.2%) controls without progressive multifocal leukoencephalopathy. The sensitivity and specificity of this PCR were 74 and 95.8%, respectively, while the positive and negative predictive values were 89.5 and 88.5%, respectively.

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Selected References

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