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. 1995 Feb;33(2):497–500. doi: 10.1128/jcm.33.2.497-500.1995

A new sensitive sandwich enzyme-linked immunosorbent assay to detect galactofuran in patients with invasive aspergillosis.

D Stynen 1, A Goris 1, J Sarfati 1, J P Latgé 1
PMCID: PMC227977  PMID: 7714217

Abstract

A double-direct sandwich enzyme-linked immunosorbent assay that uses a rat anti-galactomannan monoclonal antibody as the acceptor and detector antibody was designed. This immunoassay, which detects less than 1 ng of galactomannan per ml, was assessed in a retrospective study with samples from patients with invasive aspergillosis. Serum is more appropriate than urine for use in the search for circulating galactomannan. Antigenemia does not have a transient character. Galactomannan can be detected at least 39 days before the death of the patients.

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Selected References

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