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. 1995 Mar;33(3):541–544. doi: 10.1128/jcm.33.3.541-544.1995

Borrelia burgdorferi in an urban environment: white-tailed deer with infected ticks and antibodies.

L A Magnarelli 1, A Denicola 1, K C Stafford 3rd 1, J F Anderson 1
PMCID: PMC227987  PMID: 7751354

Abstract

Ticks and blood samples were collected from white-tailed deer (Odocoileus virginianus) in forests located in an insular, urban area of Bridgeport, Conn., and in rural south central Connecticut during 1992 and 1993. Immature and adult Ixodes scapularis ticks were tested for Borrelia burgdorferi, the etiologic agent of Lyme borreliosis, by indirect fluorescent-antibody staining methods. Deer sera were analyzed for antibodies to this bacterium by an enzyme-linked immunosorbent assay. Infected ticks parasitized deer in Bridgeport from May through December; the prevalence of infection varied from 1.1% of 93 larvae to 28.1% of 114 adult females. The percentages of infected males (10.5% of 380 ticks) and females (13.7% of 328 ticks) were relatively lower in south central Connecticut. In antibody tests, the prevalence of seropositive specimens collected in Bridgeport (61% of 146 serum specimens) was more than twofold greater than that of specimens obtained in south central Connecticut (26.7% of 116 serum specimens). Foci for Lyme borreliosis can occur in forested, urban settings as well as in rural areas if there are ticks, rodents, birds, and large mammals present. Human exposure to ticks in such sites should be considered as a possible source of B. burgdorferi infection.

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Selected References

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  1. Anderson J. F., Duray P. H., Magnarelli L. A. Borrelia burgdorferi and Ixodes dammini prevalent in the greater Philadelphia area. J Infect Dis. 1990 Apr;161(4):811–812. doi: 10.1093/infdis/161.4.811. [DOI] [PubMed] [Google Scholar]
  2. Anderson J. F., Johnson R. C., Magnarelli L. A., Hyde F. W., Andreadis T. G. New infectious spirochete isolated from short-tailed shrews and white-footed mice. J Clin Microbiol. 1987 Aug;25(8):1490–1494. doi: 10.1128/jcm.25.8.1490-1494.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Anderson J. F., Johnson R. C., Magnarelli L. A., Hyde F. W. Culturing Borrelia burgdorferi from spleen and kidney tissues of wild-caught white-footed mice, Peromyscus leucopus. Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Dec;263(1-2):34–39. doi: 10.1016/s0176-6724(86)80099-2. [DOI] [PubMed] [Google Scholar]
  4. Anderson J. F., Johnson R. C., Magnarelli L. A., Hyde F. W. Identification of endemic foci of Lyme disease: isolation of Borrelia burgdorferi from feral rodents and ticks (Dermacentor variabilis). J Clin Microbiol. 1985 Jul;22(1):36–38. doi: 10.1128/jcm.22.1.36-38.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Anderson J. F., Johnson R. C., Magnarelli L. A., Hyde F. W. Involvement of birds in the epidemiology of the Lyme disease agent Borrelia burgdorferi. Infect Immun. 1986 Feb;51(2):394–396. doi: 10.1128/iai.51.2.394-396.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Anderson J. F., Magnarelli L. A. Epizootiology of Lyme disease-causing borreliae. Clin Dermatol. 1993 Jul-Sep;11(3):339–351. doi: 10.1016/0738-081x(93)90088-t. [DOI] [PubMed] [Google Scholar]
  7. Anderson J. F., Magnarelli L. A., LeFebvre R. B., Andreadis T. G., McAninch J. B., Perng G. C., Johnson R. C. Antigenically variable Borrelia burgdorferi isolated from cottontail rabbits and Ixodes dentatus in rural and urban areas. J Clin Microbiol. 1989 Jan;27(1):13–20. doi: 10.1128/jcm.27.1.13-20.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Anderson J. F., Magnarelli L. A., Stafford K. C., 3rd Bird-feeding ticks transstadially transmit Borrelia burgdorferi that infect Syrian hamsters. J Wildl Dis. 1990 Jan;26(1):1–10. doi: 10.7589/0090-3558-26.1.1. [DOI] [PubMed] [Google Scholar]
  9. Cartter M. L., Mshar P., Hadler J. L. The epidemiology of Lyme disease in Connecticut. Conn Med. 1989 Jun;53(6):320–323. [PubMed] [Google Scholar]
  10. Curran K. L., Fish D., Piesman J. Reduction of nymphal Ixodes dammini (Acari: Ixodidae) in a residential suburban landscape by area application of insecticides. J Med Entomol. 1993 Jan;30(1):107–113. doi: 10.1093/jmedent/30.1.107. [DOI] [PubMed] [Google Scholar]
  11. Donahue J. G., Piesman J., Spielman A. Reservoir competence of white-footed mice for Lyme disease spirochetes. Am J Trop Med Hyg. 1987 Jan;36(1):92–96. doi: 10.4269/ajtmh.1987.36.92. [DOI] [PubMed] [Google Scholar]
  12. Falco R. C., Fish D. Potential for exposure to tick bites in recreational parks in a Lyme disease endemic area. Am J Public Health. 1989 Jan;79(1):12–15. doi: 10.2105/ajph.79.1.12. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Gill J. S., McLean R. G., Shriner R. B., Johnson R. C. Serologic surveillance for the Lyme disease spirochete, Borrelia burgdorferi, in Minnesota by using white-tailed deer as sentinel animals. J Clin Microbiol. 1994 Feb;32(2):444–451. doi: 10.1128/jcm.32.2.444-451.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Godsey M. S., Jr, Amundson T. E., Burgess E. C., Schell W., Davis J. P., Kaslow R., Edelman R. Lyme disease ecology in Wisconsin: distribution and host preferences of Ixodes dammini, and prevalence of antibody to Borrelia burgdorferi in small mammals. Am J Trop Med Hyg. 1987 Jul;37(1):180–187. doi: 10.4269/ajtmh.1987.37.180. [DOI] [PubMed] [Google Scholar]
  15. Levine J. F., Wilson M. L., Spielman A. Mice as reservoirs of the Lyme disease spirochete. Am J Trop Med Hyg. 1985 Mar;34(2):355–360. doi: 10.4269/ajtmh.1985.34.355. [DOI] [PubMed] [Google Scholar]
  16. Loken K. I., Wu C. C., Johnson R. C., Bey R. F. Isolation of the Lyme disease spirochete from mammals in Minnesota. Proc Soc Exp Biol Med. 1985 Jul;179(3):300–302. doi: 10.3181/00379727-179-42100. [DOI] [PubMed] [Google Scholar]
  17. Magnarelli L. A., Anderson J. F., Apperson C. S., Fish D., Johnson R. C., Chappell W. A. Spirochetes in ticks and antibodies to Borrelia burgdorferi in white-tailed deer from Connecticut, New York State, and North Carolina. J Wildl Dis. 1986 Apr;22(2):178–188. doi: 10.7589/0090-3558-22.2.178. [DOI] [PubMed] [Google Scholar]
  18. Magnarelli L. A., Anderson J. F., Cartter M. L. Geographic distribution of white-tailed deer with ticks and antibodies to Borrelia burgdorferi in Connecticut. Yale J Biol Med. 1993 Jan-Feb;66(1):19–26. [PMC free article] [PubMed] [Google Scholar]
  19. Magnarelli L. A., Anderson J. F., Chappell W. A. Antibodies to spirochetes in white-tailed deer and prevalence of infected ticks from foci of Lyme disease in Connecticut. J Wildl Dis. 1984 Jan;20(1):21–26. doi: 10.7589/0090-3558-20.1.21. [DOI] [PubMed] [Google Scholar]
  20. Magnarelli L. A., Anderson J. F. Ticks and biting insects infected with the etiologic agent of Lyme disease, Borrelia burgdorferi. J Clin Microbiol. 1988 Aug;26(8):1482–1486. doi: 10.1128/jcm.26.8.1482-1486.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Magnarelli L. A., Oliver J. H., Jr, Hutcheson H. J., Anderson J. F. Antibodies to Borrelia burgdorferi in deer and raccoons. J Wildl Dis. 1991 Oct;27(4):562–568. doi: 10.7589/0090-3558-27.4.562. [DOI] [PubMed] [Google Scholar]
  22. Mahnke G. L., Stallknecht D. E., Greene C. E., Nettles V. F., Marks M. A. Serologic survey for antibodies to Borrelia burgdorferi in white-tailed deer in Georgia. J Wildl Dis. 1993 Apr;29(2):230–236. doi: 10.7589/0090-3558-29.2.230. [DOI] [PubMed] [Google Scholar]
  23. Stafford K. C., 3rd, Magnarelli L. A. Spatial and temporal patterns of Ixodes scapularis (Acari: Ixodidae) in southeastern Connecticut. J Med Entomol. 1993 Jul;30(4):762–771. doi: 10.1093/jmedent/30.4.762. [DOI] [PubMed] [Google Scholar]
  24. Weisbrod A. R., Johnson R. C. Lyme disease and migrating birds in the Saint Croix River Valley. Appl Environ Microbiol. 1989 Aug;55(8):1921–1924. doi: 10.1128/aem.55.8.1921-1924.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Wilson M. L., Litwin T. S., Gavin T. A., Capkanis M. C., Maclean D. C., Spielman A. Host-dependent differences in feeding and reproduction of Ixodes dammini (Acari: Ixodidae). J Med Entomol. 1990 Nov;27(6):945–954. doi: 10.1093/jmedent/27.6.945. [DOI] [PubMed] [Google Scholar]

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