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Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1995 Mar;33(3):735–737. doi: 10.1128/jcm.33.3.735-737.1995

Disseminated Microascus cirrosus infection in pediatric bone marrow transplant recipient.

K K Krisher 1, N B Holdridge 1, M M Mustafa 1, M G Rinaldi 1, D A McGough 1
PMCID: PMC228024  PMID: 7751387

Abstract

Microascus cirrosus Curzi and its associated anamorphic state, Scopulariopsis, were recovered from the cutaneous lesion of a 12-year-old male who had undergone an autologous bone marrow transplantation for acute myelogenous leukemia. Histopathology sections from the biopsied lesion demonstrated septate hyphae consistent with a fungal etiology. Radiographic studies of the lungs subsequent to progression of the lesion revealed a consolidation in the right upper lobe suggesting a primary focus of infection. While M. cirrosus is fairly abundant in nature and widely distributed in stored grains in North America, this is, to our knowledge, the first reported human infection by this species. Salient characteristics for the identification of this dematiaceous ascomycete, M. cirrosus, will be presented.

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Selected References

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  1. Agarwal G. P., Singh S. M. Microascus cinereus infection of human nail. Indian J Med Sci. 1980 Nov;34(11):263–265. [PubMed] [Google Scholar]
  2. Neglia J. P., Hurd D. D., Ferrieri P., Snover D. C. Invasive Scopulariopsis in the immunocompromised host. Am J Med. 1987 Dec;83(6):1163–1166. doi: 10.1016/0002-9343(87)90961-2. [DOI] [PubMed] [Google Scholar]
  3. Rinaldi M. G. Use of potato flakes agar in clinical mycology. J Clin Microbiol. 1982 Jun;15(6):1159–1160. doi: 10.1128/jcm.15.6.1159-1160.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Wheat L. J., Bartlett M., Ciccarelli M., Smith J. W. Opportunistic Scopulariopsis pneumonia in an immunocompromised host. South Med J. 1984 Dec;77(12):1608–1609. doi: 10.1097/00007611-198412000-00041. [DOI] [PubMed] [Google Scholar]

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