Skip to main content
Canadian Family Physician logoLink to Canadian Family Physician
. 1989 Mar;35:653–654.

Dangers of NSAIDS in the Elderly

SG Smith
PMCID: PMC2280786  PMID: 21249004

Abstract

Nsaids are the most widely prescribed of all drugs when grouped by generic categories, and they are frequently given in the treatment of musculoskeletal disorders. These drugs are known to produce serious side-effects, particulary in the elderly. The author of this article lists various categories of typical side-effects and cautions against the routine use of Nsaids, particularly in patients at risk for certain conditions and in combination with certain other types of medication.

Keywords: elderly, side-effects, contraindications

Full text

PDF
653

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Attallah A. A. Interaction of prostaglandins with diuretics. Prostaglandins. 1979 Sep;18(3):369–375. doi: 10.1016/s0090-6980(79)80055-6. [DOI] [PubMed] [Google Scholar]
  2. Boardman P. L., Hart F. D. Side-effects of indomethacin. Ann Rheum Dis. 1967 Mar;26(2):127–132. doi: 10.1136/ard.26.2.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Davis A., Day R. O., Begg E. J. Interactions between non-steroidal anti-inflammatory drugs and antihypertensives and diuretics. Aust N Z J Med. 1986 Aug;16(4):537–546. doi: 10.1111/j.1445-5994.1986.tb02031.x. [DOI] [PubMed] [Google Scholar]
  4. Dunn M. J. Nonsteroidal antiinflammatory drugs and renal function. Annu Rev Med. 1984;35:411–428. doi: 10.1146/annurev.me.35.020184.002211. [DOI] [PubMed] [Google Scholar]
  5. Garella S., Matarese R. A. Renal effects of prostaglandins and clinical adverse effects of nonsteroidal anti-inflammatory agents. Medicine (Baltimore) 1984 May;63(3):165–181. doi: 10.1097/00005792-198405000-00003. [DOI] [PubMed] [Google Scholar]
  6. Newman N. M., Ling R. S. Acetabular bone destruction related to non-steroidal anti-inflammatory drugs. Lancet. 1985 Jul 6;2(8445):11–14. doi: 10.1016/s0140-6736(85)90058-3. [DOI] [PubMed] [Google Scholar]
  7. Sedor J. R., Davidson E. W., Dunn M. J. Effects of nonsteroidal anti-inflammatory drugs in healthy subjects. Am J Med. 1986 Aug 25;81(2B):58–70. doi: 10.1016/0002-9343(86)90908-3. [DOI] [PubMed] [Google Scholar]
  8. Somerville K., Faulkner G., Langman M. Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer. Lancet. 1986 Mar 1;1(8479):462–464. doi: 10.1016/s0140-6736(86)92927-2. [DOI] [PubMed] [Google Scholar]

Articles from Canadian Family Physician are provided here courtesy of College of Family Physicians of Canada

RESOURCES