Abstract
Diagnosis and treatment of infertility, once a purely empirical process, can now be based on rational exclusion of alternatives. The author reviews the drug treatment of infertility, emphasizing ovulation induction. He also discusses the endocrine treatment of men, drug treatment of endometriosis, and antibiotic treatment of infections. The author recommends referral to a specialist when more invasive drugs, such as gonadotrophins or gonadotrophin-releasing hormone or analogue, are indicated, if the couple continues to be infertile, or when the physician suspects endometriosis.
Keywords: endocrinology, gynecology, infertility
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Selected References
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- Corenblum B., Mackin J., Taylor P. J. Ovulation induction and pregnancy in women with hypothalamic amenorrhea treated with intermittent gonadotropin-releasing hormone. J Reprod Med. 1985 Oct;30(10):736–740. [PubMed] [Google Scholar]
- Corenblum B., Taylor P. J. Long-term follow-up of hyperprolactinemic women treated with bromocriptine. Fertil Steril. 1983 Nov;40(5):596–599. doi: 10.1016/s0015-0282(16)47415-7. [DOI] [PubMed] [Google Scholar]
- Henzl M. R., Corson S. L., Moghissi K., Buttram V. C., Berqvist C., Jacobson J. Administration of nasal nafarelin as compared with oral danazol for endometriosis. A multicenter double-blind comparative clinical trial. N Engl J Med. 1988 Feb 25;318(8):485–489. doi: 10.1056/NEJM198802253180805. [DOI] [PubMed] [Google Scholar]
- Rodriguez-Rigau L. J., Smith K. D., Tcholakian R. K., Steinberger E. Effect of prednisone on plasma testosterone levels and on duration of phases of the menstrual cycle in hyperandrogenic women. Fertil Steril. 1979 Oct;32(4):408–413. doi: 10.1016/s0015-0282(16)44296-2. [DOI] [PubMed] [Google Scholar]
- Santoro N., Filicori M., Crowley W. F., Jr Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone. Endocr Rev. 1986 Feb;7(1):11–23. doi: 10.1210/edrv-7-1-11. [DOI] [PubMed] [Google Scholar]
- Schwartz M., Jewelewicz R. The use of gonadotropins for induction of ovulation. Fertil Steril. 1981 Jan;35(1):3–12. doi: 10.1016/s0015-0282(16)45249-0. [DOI] [PubMed] [Google Scholar]