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. 1995 May;33(5):1368–1370. doi: 10.1128/jcm.33.5.1368-1370.1995

Taxonomic position of deep-seated, mucosa-associated, and superficial isolates of Trichosporon cutaneum from trichosporonosis patients.

T Sugita 1, A Nishikawa 1, T Shinoda 1, H Kume 1
PMCID: PMC228168  PMID: 7615757

Abstract

Clinical isolates of Trichosporon cutaneum, the causative agent of trichosporonosis, were identified on the basis of DNA relatedness. Of the 10 strains from deep-seated and mucosa-associated infections, 9 were identified as T. asahii and 1 was identified as T. ovoides. The two superficial strains were identified as T. cutaneum and a variety of T. montevideense. These findings suggest that T. cutaneum is a heterogeneous species in clinical samples and that the causative agents of trichosporonosis exist in four or more species.

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Selected References

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  1. Adnan S., Li N., Miura H., Hashimoto Y., Yamamoto H., Ezaki T. Covalently immobilized DNA plate for luminometric DNA-DNA hybridization to identify viridans streptococci in under 2 hours. FEMS Microbiol Lett. 1993 Jan 15;106(2):139–142. doi: 10.1111/j.1574-6968.1993.tb05949.x. [DOI] [PubMed] [Google Scholar]
  2. Ando M., Arima K., Yoneda R., Tamura M. Japanese summer-type hypersensitivity pneumonitis. Geographic distribution, home environment, and clinical characteristics of 621 cases. Am Rev Respir Dis. 1991 Oct;144(4):765–769. doi: 10.1164/ajrccm/144.4.765. [DOI] [PubMed] [Google Scholar]
  3. Ando M., Sakata T., Yoshida K., Yamasaki H., Araki S., Onoue K., Shinoda T. Serotype-related antigen of Trichosporon cutaneum in the induction of summer-type hypersensitivity pneumonitis: correlation between serotype of inhalation challenge-positive antigen and that of the isolates from patients' homes. J Allergy Clin Immunol. 1990 Jan;85(1 Pt 1):36–44. doi: 10.1016/0091-6749(90)90218-s. [DOI] [PubMed] [Google Scholar]
  4. Barchiesi F., Morbiducci V., Ancarani F., Arzeni D., Scalise G. Trichosporon beigelii fungaemia in an AIDS patient. AIDS. 1993 Jan;7(1):139–140. doi: 10.1097/00002030-199301000-00030. [DOI] [PubMed] [Google Scholar]
  5. Guého E., Improvisi L., de Hoog G. S., Dupont B. Trichosporon on humans: a practical account. Mycoses. 1994 Jan-Feb;37(1-2):3–10. doi: 10.1111/j.1439-0507.1994.tb00277.x. [DOI] [PubMed] [Google Scholar]
  6. Guého E., Smith M. T., de Hoog G. S., Billon-Grand G., Christen R., Batenburg-van der Vegte W. H. Contributions to a revision of the genus Trichosporon. Antonie Van Leeuwenhoek. 1992 May;61(4):289–316. doi: 10.1007/BF00713938. [DOI] [PubMed] [Google Scholar]
  7. Guého E., Tredick J., Phaff H. J. DNA base composition and DNA relatedness among species of Trichosporon Behrend. Antonie Van Leeuwenhoek. 1984;50(1):17–32. doi: 10.1007/BF00404904. [DOI] [PubMed] [Google Scholar]
  8. Guého E., de Hoog G. S., Smith M. T. Neotypification of the genus Trichosporon. Antonie Van Leeuwenhoek. 1992 May;61(4):285–288. doi: 10.1007/BF00713937. [DOI] [PubMed] [Google Scholar]
  9. Hoy J., Hsu K. C., Rolston K., Hopfer R. L., Luna M., Bodey G. P. Trichosporon beigelii infection: a review. Rev Infect Dis. 1986 Nov-Dec;8(6):959–967. [PubMed] [Google Scholar]
  10. Kamalam A., Senthamilselvi G., Ajithadas K., Thambiah A. S. Cutaneous trichosporosis. Mycopathologia. 1988 Mar;101(3):167–175. doi: 10.1007/BF00437035. [DOI] [PubMed] [Google Scholar]
  11. Kemker B. J., Lehmann P. F., Lee J. W., Walsh T. J. Distinction of deep versus superficial clinical and nonclinical isolates of Trichosporon beigelii by isoenzymes and restriction fragment length polymorphisms of rDNA generated by polymerase chain reaction. J Clin Microbiol. 1991 Aug;29(8):1677–1683. doi: 10.1128/jcm.29.8.1677-1683.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Kobayashi M., Kotani S., Fujishita M., Taguchi H., Moriki T., Enzan H., Miyoshi I. Immunohistochemical identification of Trichosporon beigelii in histologic section by immunoperoxidase method. Am J Clin Pathol. 1988 Jan;89(1):100–105. doi: 10.1093/ajcp/89.1.100. [DOI] [PubMed] [Google Scholar]
  13. Kwon-Chung K. J., Kozel T. R., Edman J. C., Polacheck I., Ellis D., Shinoda T., Dromer F. Recent advances in biology and immunology of Cryptococcus neoformans. J Med Vet Mycol. 1992;30 (Suppl 1):133–142. [PubMed] [Google Scholar]
  14. Leaf H. L., Simberkoff M. S. Invasive trichosporonosis in a patient with the acquired immunodeficiency syndrome. J Infect Dis. 1989 Aug;160(2):356–357. doi: 10.1093/infdis/160.2.356. [DOI] [PubMed] [Google Scholar]
  15. Lee J. W., Melcher G. A., Rinaldi M. G., Pizzo P. A., Walsh T. J. Patterns of morphologic variation among isolates of Trichosporon beigelii. J Clin Microbiol. 1990 Dec;28(12):2823–2827. doi: 10.1128/jcm.28.12.2823-2827.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. McManus E. J., Jones J. M. Detection of a Trichosporon beigelii antigen cross-reactive with Cryptococcus neoformans capsular polysaccharide in serum from a patient with disseminated Trichosporon infection. J Clin Microbiol. 1985 May;21(5):681–685. doi: 10.1128/jcm.21.5.681-685.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Melcher G. P., Rinaldi M. G., Frey C. L., Drutz D. J. Demonstration, by immunoelectronmicroscopy, of a cell wall antigen in Trichosporon beigelii that cross-reacts with Cryptococcus neoformans capsular polysaccharide. J Infect Dis. 1988 Oct;158(4):901–902. doi: 10.1093/infdis/158.4.901. [DOI] [PubMed] [Google Scholar]
  18. Mizobe T., Yamasaki H., Doi K., Ando M., Onoue K. Analysis of serotype-specific antibodies to Trichosporon cutaneum types I and II in patients with summer-type hypersensitivity pneumonitis with monoclonal antibodies to serotype-related polysaccharide antigens. J Clin Microbiol. 1993 Jul;31(7):1949–1951. doi: 10.1128/jcm.31.7.1949-1951.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Mochizuki T., Sugiura H., Watanabe S., Takada M., Hodohara K., Kushima R. A case of disseminated trichosporonosis: a case report and immunohistochemical identification of fungal elements. J Med Vet Mycol. 1988;26(6):343–349. doi: 10.1080/02681218880000491. [DOI] [PubMed] [Google Scholar]
  20. Nahass G. T., Rosenberg S. P., Leonardi C. L., Penneys N. S. Disseminated infection with Trichosporon beigelii. Report of a case and review of the cutaneous and histologic manifestations. Arch Dermatol. 1993 Aug;129(8):1020–1023. doi: 10.1001/archderm.129.8.1020. [DOI] [PubMed] [Google Scholar]
  21. Restrepo B. I., Barbour A. G. Cloning of 18S and 25S rDNAs from the pathogenic fungus Cryptococcus neoformans. J Bacteriol. 1989 Oct;171(10):5596–5600. doi: 10.1128/jb.171.10.5596-5600.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Surmont I., Vergauwen B., Marcelis L., Verbist L., Verhoef G., Boogaerts M. First report of chronic meningitis caused by Trichosporon beigelii. Eur J Clin Microbiol Infect Dis. 1990 Mar;9(3):226–229. doi: 10.1007/BF01963845. [DOI] [PubMed] [Google Scholar]
  23. Takeuchi T., Kobayashi M., Moriki T., Miyoshi I. Application of a monoclonal antibody for the detection of Trichosporon beigelii in paraffin-embedded tissue sections. J Pathol. 1988 Sep;156(1):23–27. doi: 10.1002/path.1711560107. [DOI] [PubMed] [Google Scholar]
  24. Walling D. M., McGraw D. J., Merz W. G., Karp J. E., Hutchins G. M. Disseminated infection with Trichosporon beigelii. Rev Infect Dis. 1987 Sep-Oct;9(5):1013–1019. doi: 10.1093/clinids/9.5.1013. [DOI] [PubMed] [Google Scholar]
  25. Watson K. C., Kallichurum S. Brain abscess due to Trichosporon cutaneum. J Med Microbiol. 1970 Feb;3(1):191–193. doi: 10.1099/00222615-3-1-191. [DOI] [PubMed] [Google Scholar]
  26. Yamasaki H., Ando M., Sakata T., Araki S., Onoue K. Importance of serotype-related antigen in the induction of experimental hypersensitivity pneumonitis by Trichosporon cutaneum in rabbits. Correlation between granulomatous alveolitis and cellular and humoral immune responses to polysaccharide-rich antigen. Am Rev Respir Dis. 1990 Mar;141(3):734–742. doi: 10.1164/ajrccm/141.3.734. [DOI] [PubMed] [Google Scholar]

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