Abstract
Respiratory distress syndrome continues to be a major cause of neonatal morbidity and mortality. The etiology, clinical diagnosis, pathogenesis, treatment, and prognosis remain controversial. Despite this, a rational program of management is possible and slow but persistent improvement in mortality appears to result from its use. These aspects of respiratory distress syndrome (RDS) or hyaline membrane disease (HMD) are discussed in detail. Still, prevention remains the more reasonable goal. Since this depends largely on prevention of prematurity, every effort must be spent in attempts to reduce the rate of premature birth.
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- AMBRUS C. M., WEINTRAUB D. H., DUNPHY D., DOWD J. E., PICKREN J. W., NISWANDER K. R., AMBRUS J. L. Studies on hyaline membrane disease. I. The fibrinolysin system in pathogenesis and therapy. Pediatrics. 1963 Jul;32:10–24. [PubMed] [Google Scholar]
- Ambrus C. M., Weintrb D. H., Ambrus J. L. Studies on hyaine membrane disease.3. Thrapeutic trial of urokinase-activated huma plasmin. Pediatrics. 1966 Aug;38(2):231–243. [PubMed] [Google Scholar]
- CHU J., CLEMENTS J. A., COTTON E., KLAUS M. H., SWEET A. Y., THOMAS M. A., TOOLEY W. H. PRELIMINARY REPORT. THE PULMONARY HYPOPERFUSION SYNDROME. Pediatrics. 1965 May;35:733–742. [PubMed] [Google Scholar]
- COHEN M. M., WEINTRAUB D. H., LILIENFELD A. M. The relationship of pulmonary hyaline membrane to certain factors in pregnancy and delivery. Pediatrics. 1960 Jul;26:42–50. [PubMed] [Google Scholar]
- Cassady G. Plasma volume studies in low birth weight infants. Pediatrics. 1966 Dec;38(6):1020–1027. [PubMed] [Google Scholar]
- Chu J., Clements J. A., Cotton E. K., Klaus M. H., Sweet A. Y., Tooley W. H., Bradley B. L., Brandorff L. C. Neonatal pulmonary ischemia. I. Clinical and physiological studies. Pediatrics. 1967 Oct;40(4 Suppl):709–782. [PubMed] [Google Scholar]
- DRISCOLL S. G., BENIRSCHKE K., CURTIS G. W. Neonatal deaths among infants of diabetic mothers. Postmortem findings in ninety-five infants. Am J Dis Child. 1960 Dec;100:818–835. doi: 10.1001/archpedi.1960.04020040820004. [DOI] [PubMed] [Google Scholar]
- Fedrick J., Butler N. R. Certain causes of neonatal death. I. Hyaline membranes. Biol Neonate. 1970;15(34):229–255. doi: 10.1159/000240229. [DOI] [PubMed] [Google Scholar]
- HESS O. W. Factors influencing perinatal mortality in cesarean section. Am J Obstet Gynecol. 1958 Feb;75(2):376–386. doi: 10.1016/0002-9378(58)90399-5. [DOI] [PubMed] [Google Scholar]
- JAMES L. S. Physiology of respiration in newborn infants and in the respiratory distress syndrome. Pediatrics. 1959 Dec;24:1069–1101. [PubMed] [Google Scholar]
- LATHAM E. F., NESBITT R. E., Jr, ANDERSON G. W. A clinical pathological study of the newborn lung with hyaline-like membranes. Bull Johns Hopkins Hosp. 1955 May;96(5):173–198. [PubMed] [Google Scholar]
- MILLER H. C., BEHRLE F. C., SMULL N. W. Respiratory activity and function in newborn infants dying with pulmonary hyaline membranes. Pediatrics. 1958 Oct;22(4 Pt 1):665–674. [PubMed] [Google Scholar]
- ORZALESI M. M., MOTOYAMA E. K., JACOBSON H. N., KIKKAWA Y., REYNOLDS E. O., COOK C. D. THE DEVELOPMENT OF THE LUNGS OF LAMBS. Pediatrics. 1965 Mar;35:373–381. [PubMed] [Google Scholar]
- STRANG L. B., ANDERSON G. S., PLATT J. W. Neonatal death and elective caesarean section. Lancet. 1957 May 11;272(6976):954–956. doi: 10.1016/s0140-6736(57)91281-3. [DOI] [PubMed] [Google Scholar]
- Tierney D. F., Clements J. A., Trahan H. J. Rates of replacement of lecithins and alveolar instability in rat lungs. Am J Physiol. 1967 Sep;213(3):671–676. doi: 10.1152/ajplegacy.1967.213.3.671. [DOI] [PubMed] [Google Scholar]
- USHER R., MCLEAN F., MAUGHAN G. B. RESPIRATORY DISTRESS SYNDROME IN INFANTS DELIVERED BY CESAREAN SECTION. Am J Obstet Gynecol. 1964 Mar 15;88:806–815. doi: 10.1016/0002-9378(64)90616-7. [DOI] [PubMed] [Google Scholar]
- USHER R. The respiratory distress syndrome of prematurity. Clinical and therapeutic aspects. Pediatr Clin North Am. 1961 May;8:525–538. doi: 10.1016/s0031-3955(16)31125-7. [DOI] [PubMed] [Google Scholar]