Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1995 Jun;33(6):1668–1669. doi: 10.1128/jcm.33.6.1668-1669.1995

Description of feline nonsuppurative meningoencephalomyelitis ("staggering disease") and studies of its etiology.

N Nowotny 1, H Weissenböck 1
PMCID: PMC228243  PMID: 7650212

Abstract

A spontaneous neurological disease in domestic cats is described. The clinical signs included staggering gait, hind limb ataxia, and paresis. Histologically, a nonsuppurative meningoencephalomyelitis with a characteristic distribution pattern was found, indicating a viral etiology. In serum samples from diseased cats, antibodies to Borna disease virus were demonstrated.

Full Text

The Full Text of this article is available as a PDF (789.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bode L., Dürrwald R., Ludwig H. Borna virus infections in cattle associated with fatal neurological disease. Vet Rec. 1994 Sep 17;135(12):283–284. doi: 10.1136/vr.135.12.283. [DOI] [PubMed] [Google Scholar]
  2. Borland R., McDonald N. Feline encephalomyelitis. Br Vet J. 1965 Oct;121(10):479–482. doi: 10.1016/s0007-1935(17)40956-0. [DOI] [PubMed] [Google Scholar]
  3. Briese T., Schneemann A., Lewis A. J., Park Y. S., Kim S., Ludwig H., Lipkin W. I. Genomic organization of Borna disease virus. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4362–4366. doi: 10.1073/pnas.91.10.4362. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Caplazi P., Waldvogel A., Stitz L., Braun U., Ehrensperger F. Borna disease in naturally infected cattle. J Comp Pathol. 1994 Jul;111(1):65–72. doi: 10.1016/s0021-9975(05)80112-4. [DOI] [PubMed] [Google Scholar]
  5. Cubitt B., Oldstone C., de la Torre J. C. Sequence and genome organization of Borna disease virus. J Virol. 1994 Mar;68(3):1382–1396. doi: 10.1128/jvi.68.3.1382-1396.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hoff E. J., Vandevelde M. Non-suppurative encephalomyelitis in cats suggestive of a viral origin. Vet Pathol. 1981 Mar;18(2):170–180. doi: 10.1177/030098588101800204. [DOI] [PubMed] [Google Scholar]
  7. Ludwig H., Kraft W., Kao M., Gosztonyi G., Dahme E., Krey H. Borna-Virus-Infektion (Borna-Krankheit) bei natürlich und experimentell infizierten Tieren: ihre Bedeutung für Forschung und Praxis. Tierarztl Prax. 1985;13(4):421–453. [PubMed] [Google Scholar]
  8. Lundgren A. L., Czech G., Bode L., Ludwig H. Natural Borna disease in domestic animals others than horses and sheep. Zentralbl Veterinarmed B. 1993 Jun;40(4):298–303. doi: 10.1111/j.1439-0450.1993.tb00142.x. [DOI] [PubMed] [Google Scholar]
  9. Lundgren A. L. Feline non-suppurative meningoencephalomyelitis. A clinical and pathological study. J Comp Pathol. 1992 Nov;107(4):411–425. doi: 10.1016/0021-9975(92)90015-M. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Richt J. A., VandeWoude S., Zink M. C., Clements J. E., Herzog S., Stitz L., Rott R., Narayan O. Infection with Borna disease virus: molecular and immunobiological characterization of the agent. Clin Infect Dis. 1992 Jun;14(6):1240–1250. doi: 10.1093/clinids/14.6.1240. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Rott R., Herzog S., Bechter K., Frese K. Borna disease, a possible hazard for man? Arch Virol. 1991;118(3-4):143–149. doi: 10.1007/BF01314025. [DOI] [PubMed] [Google Scholar]
  12. Rott R., Herzog S., Fleischer B., Winokur A., Amsterdam J., Dyson W., Koprowski H. Detection of serum antibodies to Borna disease virus in patients with psychiatric disorders. Science. 1985 May 10;228(4700):755–756. doi: 10.1126/science.3922055. [DOI] [PubMed] [Google Scholar]
  13. Vandevelde M., Braund K. G. Polioencephalomyelitis in cats. Vet Pathol. 1979 Jul;16(4):420–427. doi: 10.1177/030098587901600404. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES