Table 1.
The Effect of Treatment with SAHA and LAQ824 on the 31P MRS Detectable Aqueous Metabolites of HT29 Human Colon Carcinoma Cells (N = 4).
| Metabolites | Control | LAQ824 | SAHA |
| PC | 19 ± 1 | 38 ± 5* | 42 ± 4† |
| GPC | 7 ± 1 | 6 ± 1 | 7 ± 1 |
| GPE | 3 ± 1 | 5 ± 1 | 5 ± 1 |
| NTP | 9 ± 1 | 13 ± 3 | 12 ± 2 |
Metabolite content is expressed as femtomole per cell. Data are expressed as mean ± SEM.
Two-tailed unpaired t test was used to compare changes between the vehicle-, SAHA-, and LAQ824-treated groups: *P = .04 and †P = .01.
PC indicates phosphocholine; GPE, glycerophosphoethanolamine; GPC, glycerophosphocholine; NTP, nucleoside triphosphate.