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. 1996 Mar;34(3):717–719. doi: 10.1128/jcm.34.3.717-719.1996

Controlled study of cytolethal distending toxin-producing Escherichia coli infections in Bangladeshi children.

M J Albert 1, S M Faruque 1, A S Faruque 1, K A Bettelheim 1, P K Neogi 1, N A Bhuiyan 1, J B Kaper 1
PMCID: PMC228876  PMID: 8904444

Abstract

The role of cytolethal distending toxin (CDT)-producing Escherichia coli, a newly described category of E. coli, in the causation of diarrhea was studied by screening E. coli isolates from 546 children < 5 years of age with diarrhea and 215 matched controls without diarrhea by using a specific DNA probe. Although CDT-positive E. coli strains were isolated from more children with diarrhea than from healthy controls (3.1 versus 0.93%), this difference did not reach statistical significance (P = 0.082). All CDT-positive strains also possessed the virulence factors of enteropathogenic E. coli or enteroaggregative E. coli isolates.

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Selected References

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