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. 1996 Jul;34(7):1808–1810. doi: 10.1128/jcm.34.7.1808-1810.1996

Search for the presence of six Mycoplasma species in peripheral blood mononuclear cells of subjects seropositive and seronegative for human immunodeficiency virus.

R Kovacic 1, V Launay 1, P Tuppin 1, A Lafeuillade 1, V Feuillie 1, L Montagnier 1, O Grau 1
PMCID: PMC229121  PMID: 8784596

Abstract

The prevalence of Mycoplasma fermentans, Mycoplasma pirum, Mycoplasma genitalium, Mycoplasma pneumoniae, Mycoplasma hominis, and Mycoplasma penetrans was investigated by using specific PCR assays with peripheral blood mononuclear cells from subjects infected or not infected with the human immunodeficiency virus (HIV). Only M. fermentans was detected in 5.8% of 154 HIV-seropositive and 11.1% of 90 HIV-seronegative subjects.

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Selected References

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  1. Ainsworth J. G., Katseni V., Hourshid S., Waldron S., Ball S., Cattell V., Taylor-Robinson D. Mycoplasma fermentans and HIV-associated nephropathy. J Infect. 1994 Nov;29(3):323–326. doi: 10.1016/s0163-4453(94)91289-0. [DOI] [PubMed] [Google Scholar]
  2. Bauer F. A., Wear D. J., Angritt P., Lo S. C. Mycoplasma fermentans (incognitus strain) infection in the kidneys of patients with acquired immunodeficiency syndrome and associated nephropathy: a light microscopic, immunohistochemical, and ultrastructural study. Hum Pathol. 1991 Jan;22(1):63–69. doi: 10.1016/0046-8177(91)90063-u. [DOI] [PubMed] [Google Scholar]
  3. Bebear C., de Barbeyrac B., Clerc M. T., Renaudin H., Fleury H. J., Dupon M., Ragnaud J. M., Morlat P. Mycoplasmas in HIV-1 seropositive patients. Lancet. 1993 Mar 20;341(8847):758–759. doi: 10.1016/0140-6736(93)90531-k. [DOI] [PubMed] [Google Scholar]
  4. Blanchard A., Montagnier L. AIDS-associated mycoplasmas. Annu Rev Microbiol. 1994;48:687–712. doi: 10.1146/annurev.mi.48.100194.003351. [DOI] [PubMed] [Google Scholar]
  5. Grau O., Kovacic R., Griffais R., Launay V., Montagnier L. Development of PCR-based assays for the detection of two human mollicute species, Mycoplasma penetrans and M. hominis. Mol Cell Probes. 1994 Apr;8(2):139–147. doi: 10.1006/mcpr.1994.1019. [DOI] [PubMed] [Google Scholar]
  6. Grau O., Kovacic R., Griffais R., Montagnier L. Development of a selective and sensitive polymerase chain reaction assay for the detection of Mycoplasma pirum. FEMS Microbiol Lett. 1993 Feb 1;106(3):327–333. doi: 10.1111/j.1574-6968.1993.tb05984.x. [DOI] [PubMed] [Google Scholar]
  7. Grau O., Slizewicz B., Tuppin P., Launay V., Bourgeois E., Sagot N., Moynier M., Lafeuillade A., Bachelez H., Clauvel J. P. Association of Mycoplasma penetrans with human immunodeficiency virus infection. J Infect Dis. 1995 Sep;172(3):672–681. doi: 10.1093/infdis/172.3.672. [DOI] [PubMed] [Google Scholar]
  8. Hawkins R. E., Rickman L. S., Vermund S. H., Carl M. Association of mycoplasma and human immunodeficiency virus infection: detection of amplified Mycoplasma fermentans DNA in blood. J Infect Dis. 1992 Mar;165(3):581–585. doi: 10.1093/infdis/165.3.581. [DOI] [PubMed] [Google Scholar]
  9. Jensen J. S., Uldum S. A., Søndergård-Andersen J., Vuust J., Lind K. Polymerase chain reaction for detection of Mycoplasma genitalium in clinical samples. J Clin Microbiol. 1991 Jan;29(1):46–50. doi: 10.1128/jcm.29.1.46-50.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Katseni V. L., Gilroy C. B., Ryait B. K., Ariyoshi K., Bieniasz P. D., Weber J. N., Taylor-Robinson D. Mycoplasma fermentans in individuals seropositive and seronegative for HIV-1. Lancet. 1993 Jan 30;341(8840):271–273. doi: 10.1016/0140-6736(93)92617-3. [DOI] [PubMed] [Google Scholar]
  11. Lo S. C., Hayes M. M., Tully J. G., Wang R. Y., Kotani H., Pierce P. F., Rose D. L., Shih J. W. Mycoplasma penetrans sp. nov., from the urogenital tract of patients with AIDS. Int J Syst Bacteriol. 1992 Jul;42(3):357–364. doi: 10.1099/00207713-42-3-357. [DOI] [PubMed] [Google Scholar]
  12. Lo S. C., Hayes M. M., Wang R. Y., Pierce P. F., Kotani H., Shih J. W. Newly discovered mycoplasma isolated from patients infected with HIV. Lancet. 1991 Dec 7;338(8780):1415–1418. doi: 10.1016/0140-6736(91)92721-d. [DOI] [PubMed] [Google Scholar]
  13. Lo S. C. Isolation and identification of a novel virus from patients with AIDS. Am J Trop Med Hyg. 1986 Jul;35(4):675–676. doi: 10.4269/ajtmh.1986.35.675. [DOI] [PubMed] [Google Scholar]
  14. Lo S. C., Shih J. W., Newton P. B., 3rd, Wong D. M., Hayes M. M., Benish J. R., Wear D. J., Wang R. Y. Virus-like infectious agent (VLIA) is a novel pathogenic mycoplasma: Mycoplasma incognitus. Am J Trop Med Hyg. 1989 Nov;41(5):586–600. doi: 10.4269/ajtmh.1989.41.586. [DOI] [PubMed] [Google Scholar]
  15. Macon W. R., Lo S. C., Poiesz B. J., Montefiori D. C., Dawson M. S., Mason T. E., Michael P. R., Cohen A. G., Davis C. M., Cousar J. B. Acquired immunodeficiency syndrome-like illness associated with systemic Mycoplasma fermentans infection in a human immunodeficiency virus-negative homosexual man. Hum Pathol. 1993 May;24(5):554–558. doi: 10.1016/0046-8177(93)90169-h. [DOI] [PubMed] [Google Scholar]
  16. McCormack W. M., Rosner B., Lee Y. H., Rankin J. S., Lin J. S. Isolation of genital mycoplasmas from blood obtained shortly after vaginal delivery. Lancet. 1975 Mar 15;1(7907):596–599. doi: 10.1016/s0140-6736(75)91881-4. [DOI] [PubMed] [Google Scholar]
  17. Saillard C., Carle P., Bové J. M., Bébéar C., Lo S. C., Shih J. W., Wang R. Y., Rose D. L., Tully J. G. Genetic and serologic relatedness between Mycoplasma fermentans strains and a mycoplasma recently identified in tissues of AIDS and non-AIDS patients. Res Virol. 1990 May-Jun;141(3):385–395. doi: 10.1016/0923-2516(90)90010-g. [DOI] [PubMed] [Google Scholar]
  18. Wallace R. J., Jr, Alpert S., Browne K., Lin J. S., McCormack W. M. Isolation of Mycoplasma hominis from blood cultures in patients with postpartum fever. Obstet Gynecol. 1978 Feb;51(2):181–185. [PubMed] [Google Scholar]
  19. Wang R. Y., Hu W. S., Dawson M. S., Shih J. W., Lo S. C. Selective detection of Mycoplasma fermentans by polymerase chain reaction and by using a nucleotide sequence within the insertion sequence-like element. J Clin Microbiol. 1992 Jan;30(1):245–248. doi: 10.1128/jcm.30.1.245-248.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Wang R. Y., Shih J. W., Weiss S. H., Grandinetti T., Pierce P. F., Lange M., Alter H. J., Wear D. J., Davies C. L., Mayur R. K. Mycoplasma penetrans infection in male homosexuals with AIDS: high seroprevalence and association with Kaposi's sarcoma. Clin Infect Dis. 1993 Oct;17(4):724–729. doi: 10.1093/clinids/17.4.724. [DOI] [PubMed] [Google Scholar]

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