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. 1996 Jul;34(7):1821–1824. doi: 10.1128/jcm.34.7.1821-1824.1996

Oerskovia xanthineolytica infection of a prosthetic joint: case report and review.

R D Harrington 1, C G Lewis 1, J Aslanzadeh 1, P Stelmach 1, A E Woolfrey 1
PMCID: PMC229126  PMID: 8784601

Abstract

Oerskovia spp. are gram-positive, Nocardia-like bacilli which inhabit the soil and rarely cause human infections. Previously reported cases of Oerskovia infection have been characterized by a nonaggressive course and an association with foreign bodies. We report the first case of a patient with a prosthetic joint infection due to Oerskovia xanthineolytica. Our patient presented with a prolonged, indolent course and was thought to have aseptic loosening of his prosthesis until the time of surgery. He was cured of his infection by removal of the prosthesis, antibiotic therapy, and delayed reimplantation. Review of the previous 10 reported cases of Oerskovia infection in humans supports the recommendation that foreign-body-associated infections should be treated with a strategy that includes removal of the foreign material.

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Selected References

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  1. Berd D. Laboratory identification of clinically important aerobic actinomycetes. Appl Microbiol. 1973 Apr;25(4):665–681. doi: 10.1128/am.25.4.665-681.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cruickshank J. G., Gawler A. H., Shaldon C. Oerskovia species: rare opportunistic pathogens. J Med Microbiol. 1979 Nov;12(4):513–515. doi: 10.1099/00222615-12-4-513. [DOI] [PubMed] [Google Scholar]
  3. Gristina A. G., Kolkin J. Current concepts review. Total joint replacement and sepsis. J Bone Joint Surg Am. 1983 Jan;65(1):128–134. [PubMed] [Google Scholar]
  4. Guss W. J., Ament M. E. Oerskovia infection caused by contaminated home parenteral nutrition solution. Arch Intern Med. 1989 Jun;149(6):1457–1458. [PubMed] [Google Scholar]
  5. Hussain Z., Gonder J. R., Lannigan R., Stoakes L. Endophthalmitis due to Oerskovia xanthineolytica. Can J Ophthalmol. 1987 Jun;22(4):234–236. [PubMed] [Google Scholar]
  6. Kailath E. J., Goldstein E., Wagner F. H. Meningitis caused by Oerskovia xanthineolytica. Am J Med Sci. 1988 Mar;295(3):216–217. doi: 10.1097/00000441-198803000-00010. [DOI] [PubMed] [Google Scholar]
  7. LeProwse C. R., McNeil M. M., McCarty J. M. Catheter-related bacteremia caused by Oerskovia turbata. J Clin Microbiol. 1989 Mar;27(3):571–572. doi: 10.1128/jcm.27.3.571-572.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. McDonald C. L., Chapin-Robertson K., Dill S. R., Martino R. L. Oerskovia xanthineolytica bacteremia in an immunocompromised patient with pneumonia. Diagn Microbiol Infect Dis. 1994 Apr;18(4):259–261. doi: 10.1016/0732-8893(94)90029-9. [DOI] [PubMed] [Google Scholar]
  9. McNeil M. M., Brown J. M., Jarvis W. R., Ajello L. Comparison of species distribution and antimicrobial susceptibility of aerobic actinomycetes from clinical specimens. Rev Infect Dis. 1990 Sep-Oct;12(5):778–783. doi: 10.1093/clinids/12.5.778. [DOI] [PubMed] [Google Scholar]
  10. Prauser H., Lechevalier M. P., Lechevalier H. Description of Oerskovia gen. n. to harbor Orskov's motile nocardia. Appl Microbiol. 1970 Mar;19(3):534–534. doi: 10.1128/am.19.3.534-534.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Reina J., Llompart I., Altés J. Absceso axilar producido por Oerskovia turbata en un paciente de SIDA. Rev Clin Esp. 1991 May;188(9):485–486. [PubMed] [Google Scholar]
  12. Reller L. B., Maddoux G. L., Eckman M. R., Pappas G. Bacterial endocarditis caused by Oerskovia turbata. Ann Intern Med. 1975 Nov;83(5):664–666. doi: 10.7326/0003-4819-83-5-664. [DOI] [PubMed] [Google Scholar]
  13. Rihs J. D., McNeil M. M., Brown J. M., Yu V. L. Oerskovia xanthineolytica implicated in peritonitis associated with peritoneal dialysis: case report and review of Oerskovia infections in humans. J Clin Microbiol. 1990 Sep;28(9):1934–1937. doi: 10.1128/jcm.28.9.1934-1937.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Sukapure R. S., Lechevalier M. P., Reber H., Higgins M. L., Lechevalier H. A., Prauser H. Motile nocardoid Actinomycetales. Appl Microbiol. 1970 Mar;19(3):527–533. doi: 10.1128/am.19.3.527-533.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Truant A. L., Satishchandran V., Eisenstaedt R., Richman P., McNeil M. M. Oerskovia xanthineolytica and methicillin-resistant Staphylococcus aureus in a patient with cirrhosis and variceal hemorrhage. Eur J Clin Microbiol Infect Dis. 1992 Oct;11(10):950–951. doi: 10.1007/BF01962383. [DOI] [PubMed] [Google Scholar]

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