Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1996 Jul;34(7):1859–1862. doi: 10.1128/jcm.34.7.1859-1862.1996

A novel genital human papillomavirus (HPV), HPV type 74, found in immunosuppressed patients.

M Longuet 1, P Cassonnet 1, G Orth 1
PMCID: PMC229138  PMID: 8784613

Abstract

The genome of a novel human papillomavirus (HPV) type, HPV74, was cloned from an iatrogenically immunosuppressed woman with persisting low-grade vaginal intraepithelial neoplasia. HPV74 was found to be phylogenetically related to the low-risk HPV types 6, 11, 44, and 55. HPV74 or a variant of this type was found in specimens from three additional immunosuppressed women but not in about 3,000 anogenital specimens from immunocompetent patients.

Full Text

The Full Text of this article is available as a PDF (324.2 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alloub M. I., Barr B. B., McLaren K. M., Smith I. W., Bunney M. H., Smart G. E. Human papillomavirus infection and cervical intraepithelial neoplasia in women with renal allografts. BMJ. 1989 Jan 21;298(6667):153–156. doi: 10.1136/bmj.298.6667.153. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Beaudenon S., Kremsdorf D., Obalek S., Jablonska S., Pehau-Arnaudet G., Croissant O., Orth G. Plurality of genital human papillomaviruses: characterization of two new types with distinct biological properties. Virology. 1987 Dec;161(2):374–384. doi: 10.1016/0042-6822(87)90130-9. [DOI] [PubMed] [Google Scholar]
  3. Bernard H. U., Chan S. Y., Manos M. M., Ong C. K., Villa L. L., Delius H., Peyton C. L., Bauer H. M., Wheeler C. M. Identification and assessment of known and novel human papillomaviruses by polymerase chain reaction amplification, restriction fragment length polymorphisms, nucleotide sequence, and phylogenetic algorithms. J Infect Dis. 1994 Nov;170(5):1077–1085. doi: 10.1093/infdis/170.5.1077. [DOI] [PubMed] [Google Scholar]
  4. Bosch F. X., Manos M. M., Muñoz N., Sherman M., Jansen A. M., Peto J., Schiffman M. H., Moreno V., Kurman R., Shah K. V. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst. 1995 Jun 7;87(11):796–802. doi: 10.1093/jnci/87.11.796. [DOI] [PubMed] [Google Scholar]
  5. Chan S. Y., Delius H., Halpern A. L., Bernard H. U. Analysis of genomic sequences of 95 papillomavirus types: uniting typing, phylogeny, and taxonomy. J Virol. 1995 May;69(5):3074–3083. doi: 10.1128/jvi.69.5.3074-3083.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Dartmann K., Schwarz E., Gissmann L., zur Hausen H. The nucleotide sequence and genome organization of human papilloma virus type 11. Virology. 1986 May;151(1):124–130. doi: 10.1016/0042-6822(86)90110-8. [DOI] [PubMed] [Google Scholar]
  7. Favre M., Kremsdorf D., Jablonska S., Obalek S., Pehau-Arnaudet G., Croissant O., Orth G. Two new human papillomavirus types (HPV54 and 55) characterized from genital tumours illustrate the plurality of genital HPVs. Int J Cancer. 1990 Jan 15;45(1):40–46. doi: 10.1002/ijc.2910450109. [DOI] [PubMed] [Google Scholar]
  8. Koutsky L. A., Galloway D. A., Holmes K. K. Epidemiology of genital human papillomavirus infection. Epidemiol Rev. 1988;10:122–163. doi: 10.1093/oxfordjournals.epirev.a036020. [DOI] [PubMed] [Google Scholar]
  9. Longuet M., Beaudenon S., Orth G. Two novel genital human papillomavirus (HPV) types, HPV68 and HPV70, related to the potentially oncogenic HPV39. J Clin Microbiol. 1996 Mar;34(3):738–744. doi: 10.1128/jcm.34.3.738-744.1996. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Lorincz A. T., Reid R., Jenson A. B., Greenberg M. D., Lancaster W., Kurman R. J. Human papillomavirus infection of the cervix: relative risk associations of 15 common anogenital types. Obstet Gynecol. 1992 Mar;79(3):328–337. doi: 10.1097/00006250-199203000-00002. [DOI] [PubMed] [Google Scholar]
  11. Lörincz A. T., Quinn A. P., Goldsborough M. D., Schmidt B. J., Temple G. F. Cloning and partial DNA sequencing of two new human papillomavirus types associated with condylomas and low-grade cervical neoplasia. J Virol. 1989 Jun;63(6):2829–2834. doi: 10.1128/jvi.63.6.2829-2834.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Schiffman M. H., Bauer H. M., Hoover R. N., Glass A. G., Cadell D. M., Rush B. B., Scott D. R., Sherman M. E., Kurman R. J., Wacholder S. Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst. 1993 Jun 16;85(12):958–964. doi: 10.1093/jnci/85.12.958. [DOI] [PubMed] [Google Scholar]
  13. Schwarz E., Dürst M., Demankowski C., Lattermann O., Zech R., Wolfsperger E., Suhai S., zur Hausen H. DNA sequence and genome organization of genital human papillomavirus type 6b. EMBO J. 1983;2(12):2341–2348. doi: 10.1002/j.1460-2075.1983.tb01744.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Seedorf K., Krämmer G., Dürst M., Suhai S., Röwekamp W. G. Human papillomavirus type 16 DNA sequence. Virology. 1985 Aug;145(1):181–185. doi: 10.1016/0042-6822(85)90214-4. [DOI] [PubMed] [Google Scholar]
  15. Short J. M., Fernandez J. M., Sorge J. A., Huse W. D. Lambda ZAP: a bacteriophage lambda expression vector with in vivo excision properties. Nucleic Acids Res. 1988 Aug 11;16(15):7583–7600. doi: 10.1093/nar/16.15.7583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Thompson J. D., Higgins D. G., Gibson T. J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994 Nov 11;22(22):4673–4680. doi: 10.1093/nar/22.22.4673. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Van Ranst M., Fuse A., Fiten P., Beuken E., Pfister H., Burk R. D., Opdenakker G. Human papillomavirus type 13 and pygmy chimpanzee papillomavirus type 1: comparison of the genome organizations. Virology. 1992 Oct;190(2):587–596. doi: 10.1016/0042-6822(92)90896-w. [DOI] [PubMed] [Google Scholar]
  18. de Villiers E. M. Human pathogenic papillomavirus types: an update. Curr Top Microbiol Immunol. 1994;186:1–12. doi: 10.1007/978-3-642-78487-3_1. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES