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. 1996 Oct;34(10):2585–2587. doi: 10.1128/jcm.34.10.2585-2587.1996

Gastric mucormycosis due to Rhizopus oryzae in a renal transplant recipient.

S Winkler 1, S Susani 1, B Willinger 1, R Apsner 1, A R Rosenkranz 1, R Pötzi 1, G A Berlakovich 1, E Pohanka 1
PMCID: PMC229322  PMID: 8880524

Abstract

Gastric mucormycosis is a rare disease with a reported fatal outcome of 98%. Manifestations range from colonization of peptic ulcers to infiltrative disease with vascular invasion and dissemination. In our renal transplant patient a deep gastric ulceration infected with Rhizopus oryzae (class Zygomycetes), which is known to be an agent of mucormycosis, was diagnosed in the early posttransplant period after antirejection therapy. The infection was successfully managed with amphotericin B and omeprazole.

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Selected References

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  1. Brullet E., Andreu X., Elias J., Roig J., Cervantes M. Gastric mucormycosis in a patient with acquired immunodeficiency syndrome. Gastrointest Endosc. 1993 Jan-Feb;39(1):106–107. doi: 10.1016/s0016-5107(93)70033-4. [DOI] [PubMed] [Google Scholar]
  2. Calle S., Klatsky S. Intestinal phycomycosis (mucormycosis). Am J Clin Pathol. 1966 Mar;45(3):264–272. doi: 10.1093/ajcp/45.3.264. [DOI] [PubMed] [Google Scholar]
  3. Chinn R. Y., Diamond R. D. Generation of chemotactic factors by Rhizopus oryzae in the presence and absence of serum: relationship to hyphal damage mediated by human neutrophils and effects of hyperglycemia and ketoacidosis. Infect Immun. 1982 Dec;38(3):1123–1129. doi: 10.1128/iai.38.3.1123-1129.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Goldblum S. E., Reed W. P. Host defenses and immunologic alterations associated with chronic hemodialysis. Ann Intern Med. 1980 Oct;93(4):597–613. doi: 10.7326/0003-4819-93-4-597. [DOI] [PubMed] [Google Scholar]
  5. Ingram C. W., Sennesh J., Cooper J. N., Perfect J. R. Disseminated zygomycosis: report of four cases and review. Rev Infect Dis. 1989 Sep-Oct;11(5):741–754. doi: 10.1093/clinids/11.5.741. [DOI] [PubMed] [Google Scholar]
  6. Jorens P. G., Boelaert J. R., Halloy V., Zamora R., Schneider Y. J., Herman A. G. Human and rat macrophages mediate fungistatic activity against Rhizopus species differently: in vitro and ex vivo studies. Infect Immun. 1995 Nov;63(11):4489–4494. doi: 10.1128/iai.63.11.4489-4494.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lawson H. H., Schmaman A. Gastric phycomycosis. Br J Surg. 1974 Sep;61(9):743–746. doi: 10.1002/bjs.1800610918. [DOI] [PubMed] [Google Scholar]
  8. Lyon D. T., Schubert T. T., Mantia A. G., Kaplan M. H. Phycomycosis of the gastrointestinal tract. Am J Gastroenterol. 1979 Oct;72(4):379–394. [PubMed] [Google Scholar]
  9. Meyer R. D., Rosen P., Armstrong D. Phycomycosis complicating leukemia and lymphoma. Ann Intern Med. 1972 Dec;77(6):871–879. doi: 10.7326/0003-4819-77-6-871. [DOI] [PubMed] [Google Scholar]
  10. Morduchowicz G., Shmueli D., Shapira Z., Cohen S. L., Yussim A., Block C. S., Rosenfeld J. B., Pitlik S. D. Rhinocerebral mucormycosis in renal transplant recipients: report of three cases and review of the literature. Rev Infect Dis. 1986 May-Jun;8(3):441–446. doi: 10.1093/clinids/8.3.441. [DOI] [PubMed] [Google Scholar]
  11. Mucormycosis. Ann Intern Med. 1980 Jul;93(1):93–108. doi: 10.7326/0003-4819-93-1-93. [DOI] [PubMed] [Google Scholar]
  12. NEAME P., RAYNER D. Mucormycosis. A report on twenty-two cases. Arch Pathol. 1960 Aug;70:261–268. [PubMed] [Google Scholar]
  13. Paya C. V. Fungal infections in solid-organ transplantation. Clin Infect Dis. 1993 May;16(5):677–688. doi: 10.1093/clind/16.5.677. [DOI] [PubMed] [Google Scholar]
  14. Thomson S. R., Bade P. G., Taams M., Chrystal V. Gastrointestinal mucormycosis. Br J Surg. 1991 Aug;78(8):952–954. doi: 10.1002/bjs.1800780819. [DOI] [PubMed] [Google Scholar]
  15. Warnock D. W. Fungal complications of transplantation: diagnosis, treatment and prevention. J Antimicrob Chemother. 1995 Oct;36 (Suppl B):73–90. doi: 10.1093/jac/36.suppl_b.73. [DOI] [PubMed] [Google Scholar]
  16. Windus D. W., Stokes T. J., Julian B. A., Fenves A. Z. Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine. Ann Intern Med. 1987 Nov;107(5):678–680. doi: 10.7326/0003-4819-107-5-678. [DOI] [PubMed] [Google Scholar]

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