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. 1997 Mar;35(3):745–750. doi: 10.1128/jcm.35.3.745-750.1997

Genetic analysis of a meningococcal population based on polymorphism of the pilA-pilB locus: a molecular approach for meningococcal epidemiology.

M Guibourdenche 1, D Giorgini 1, A Guèye 1, M Larribe 1, J Y Riou 1, M K Taha 1
PMCID: PMC229664  PMID: 9041426

Abstract

The genetic relationships between 88 meningococcal strains were analyzed by using the polymorphism of the pilA gene and the multilocus enzyme electrophoresis. While a good agreement was observed, correlation with antigenic formula (serogroup, serotype, and serosubtype) was incomplete. The inadequacy of serological classification alone in outbreak surveillance may be overcome by DNA-based approaches.

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Selected References

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