Abstract
Neurotoxigenic Clostridium butyricum was isolated from the food implicated in an outbreak of clinically diagnosed type E botulism in China. PCR assay showed that the isolate (LCL 155) contained the type E botulinum toxin gene. This appears to be the first report of neurotoxigenic C. butyricum causing food-borne botulism.
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Selected References
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- Aureli P., Fenicia L., Pasolini B., Gianfranceschi M., McCroskey L. M., Hatheway C. L. Two cases of type E infant botulism caused by neurotoxigenic Clostridium butyricum in Italy. J Infect Dis. 1986 Aug;154(2):207–211. doi: 10.1093/infdis/154.2.207. [DOI] [PubMed] [Google Scholar]
- Giménez J. A., Sugiyama H. Comparison of toxins of Clostridium butyricum and Clostridium botulinum type E. Infect Immun. 1988 Apr;56(4):926–929. doi: 10.1128/iai.56.4.926-929.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hall J. D., McCroskey L. M., Pincomb B. J., Hatheway C. L. Isolation of an organism resembling Clostridium barati which produces type F botulinal toxin from an infant with botulism. J Clin Microbiol. 1985 Apr;21(4):654–655. doi: 10.1128/jcm.21.4.654-655.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kozaki S., Onimaru J., Kamata Y., Sakaguchi G. Immunological characterization of Clostridium butyricum neurotoxin and its trypsin-induced fragment by use of monoclonal antibodies against Clostridium botulinum type E neurotoxin. Infect Immun. 1991 Jan;59(1):457–459. doi: 10.1128/iai.59.1.457-459.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McCroskey L. M., Hatheway C. L., Fenicia L., Pasolini B., Aureli P. Characterization of an organism that produces type E botulinal toxin but which resembles Clostridium butyricum from the feces of an infant with type E botulism. J Clin Microbiol. 1986 Jan;23(1):201–202. doi: 10.1128/jcm.23.1.201-202.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Poulet S., Hauser D., Quanz M., Niemann H., Popoff M. R. Sequences of the botulinal neurotoxin E derived from Clostridium botulinum type E (strain Beluga) and Clostridium butyricum (strains ATCC 43181 and ATCC 43755). Biochem Biophys Res Commun. 1992 Feb 28;183(1):107–113. doi: 10.1016/0006-291x(92)91615-w. [DOI] [PubMed] [Google Scholar]
- Szabo E. A., Pemberton J. M., Desmarchelier P. M. Detection of the genes encoding botulinum neurotoxin types A to E by the polymerase chain reaction. Appl Environ Microbiol. 1993 Sep;59(9):3011–3020. doi: 10.1128/aem.59.9.3011-3020.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamakawa K., Nakamura S. Prevalence of Clostridium botulinum type E and coexistence of C. botulinum nonproteolytic type B in the river soil of Japan. Microbiol Immunol. 1992;36(6):583–591. doi: 10.1111/j.1348-0421.1992.tb02058.x. [DOI] [PubMed] [Google Scholar]