Abstract
Comparative sequence analysis of a 30-bp segment in the quinolone resistance-determining region of campylobacters not only allows for the detection of base changes associated with resistance but also is a powerful tool for species identification based on silent mutations.
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- Amann R. I., Ludwig W., Schleifer K. H. Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol Rev. 1995 Mar;59(1):143–169. doi: 10.1128/mr.59.1.143-169.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fredricks D. N., Relman D. A. Sequence-based identification of microbial pathogens: a reconsideration of Koch's postulates. Clin Microbiol Rev. 1996 Jan;9(1):18–33. doi: 10.1128/cmr.9.1.18. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Guillemin I., Cambau E., Jarlier V. Sequences of conserved region in the A subunit of DNA gyrase from nine species of the genus Mycobacterium: phylogenetic analysis and implication for intrinsic susceptibility to quinolones. Antimicrob Agents Chemother. 1995 Sep;39(9):2145–2149. doi: 10.1128/aac.39.9.2145. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Husmann M., Gries C., Jehnichen P., Woelfel T., Gerken G., Ludwig W., Bhakdi S. Helicobacter sp. strain Mainz isolated from an AIDS patient with septic arthritis: case report and nonradioactive analysis of 16S rRNA sequence. J Clin Microbiol. 1994 Dec;32(12):3037–3039. doi: 10.1128/jcm.32.12.3037-3039.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kiehlbauch J. A., Brenner D. J., Cameron D. N., Steigerwalt A. G., Makowski J. M., Baker C. N., Patton C. M., Wachsmuth I. K. Genotypic and phenotypic characterization of Helicobacter cinaedi and Helicobacter fennelliae strains isolated from humans and animals. J Clin Microbiol. 1995 Nov;33(11):2940–2947. doi: 10.1128/jcm.33.11.2940-2947.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kirschner P., Springer B., Vogel U., Meier A., Wrede A., Kiekenbeck M., Bange F. C., Böttger E. C. Genotypic identification of mycobacteria by nucleic acid sequence determination: report of a 2-year experience in a clinical laboratory. J Clin Microbiol. 1993 Nov;31(11):2882–2889. doi: 10.1128/jcm.31.11.2882-2889.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moore R. A., Beckthold B., Wong S., Kureishi A., Bryan L. E. Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori. Antimicrob Agents Chemother. 1995 Jan;39(1):107–111. doi: 10.1128/aac.39.1.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Olsen G. J., Woese C. R. Ribosomal RNA: a key to phylogeny. FASEB J. 1993 Jan;7(1):113–123. doi: 10.1096/fasebj.7.1.8422957. [DOI] [PubMed] [Google Scholar]
- On S. L. Identification methods for campylobacters, helicobacters, and related organisms. Clin Microbiol Rev. 1996 Jul;9(3):405–422. doi: 10.1128/cmr.9.3.405. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sacks L. V., Labriola A. M., Gill V. J., Gordin F. M. Use of ciprofloxacin for successful eradication of bacteremia due to Campylobacter cinaedi in a human immunodeficiency virus-infected person. Rev Infect Dis. 1991 Nov-Dec;13(6):1066–1068. doi: 10.1093/clinids/13.6.1066. [DOI] [PubMed] [Google Scholar]
- Wang Y., Huang W. M., Taylor D. E. Cloning and nucleotide sequence of the Campylobacter jejuni gyrA gene and characterization of quinolone resistance mutations. Antimicrob Agents Chemother. 1993 Mar;37(3):457–463. doi: 10.1128/aac.37.3.457. [DOI] [PMC free article] [PubMed] [Google Scholar]