Abstract
In order to investigate the role of Helcococcus kunzii as a colonizer of skin and as a possible participant in diabetic foot ulcers, we used a selective medium to culture both lower- and upper-extremity skin from a study group of podiatry patients (60 diabetics and 60 nondiabetics) and a control group of 50 healthy volunteers. Although differences in colonization were not statistically significant, a trend toward higher colonization rates in the group of podiatry patients was noted. H. kunzii appears to preferentially colonize the skin of the feet, and while its pathogenic role in diabetic foot ulcers is difficult to establish, it may be a previously unrecognized component of the polymicrobial flora characteristically isolated from patients with these infections.
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Selected References
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- Borrero E., Rossini M., Jr Bacteriology of 100 consecutive diabetic foot infections and in vitro susceptibility to ampicillin/sulbactam versus cefoxitin. Angiology. 1992 Apr;43(4):357–361. doi: 10.1177/000331979204300411. [DOI] [PubMed] [Google Scholar]
- Caliendo A. M., Jordan C. D., Ruoff K. L. Helcococcus, a new genus of catalase-negative, gram-positive cocci isolated from clinical specimens. J Clin Microbiol. 1995 Jun;33(6):1638–1638. doi: 10.1128/jcm.33.6.1638-1638.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Collins M. D., Facklam R. R., Rodrigues U. M., Ruoff K. L. Phylogenetic analysis of some Aerococcus-like organisms from clinical sources: description of Helcococcus kunzii gen. nov., sp. nov. Int J Syst Bacteriol. 1993 Jul;43(3):425–429. doi: 10.1099/00207713-43-3-425. [DOI] [PubMed] [Google Scholar]
- Eckman M. H., Greenfield S., Mackey W. C., Wong J. B., Kaplan S., Sullivan L., Dukes K., Pauker S. G. Foot infections in diabetic patients. Decision and cost-effectiveness analyses. JAMA. 1995 Mar 1;273(9):712–720. [PubMed] [Google Scholar]
- Facklam R., Elliott J. A. Identification, classification, and clinical relevance of catalase-negative, gram-positive cocci, excluding the streptococci and enterococci. Clin Microbiol Rev. 1995 Oct;8(4):479–495. doi: 10.1128/cmr.8.4.479. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gentry L. O. Diagnosis and management of the diabetic foot ulcer. J Antimicrob Chemother. 1993 Jul;32 (Suppl A):77–89. doi: 10.1093/jac/32.suppl_a.77. [DOI] [PubMed] [Google Scholar]
- Peel M. M., Davis J. M., Griffin K. J., Freedman D. L. Helcococcus kunzii as sole isolate from an infected sebaceous cyst. J Clin Microbiol. 1997 Jan;35(1):328–329. doi: 10.1128/jcm.35.1.328-329.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]