Skip to main content
Journal of Clinical Microbiology logoLink to Journal of Clinical Microbiology
. 1997 Nov;35(11):2981–2982. doi: 10.1128/jcm.35.11.2981-2982.1997

Virulence patterns of Escherichia coli K1 strains associated with neonatal meningitis.

E Bingen 1, S Bonacorsi 1, N Brahimi 1, E Denamur 1, J Elion 1
PMCID: PMC230101  PMID: 9350773

Abstract

The prevalence of the ibe10 gene, of the pap, afa, and sfa adhesin-encoding operons, and of a 14.9-kb rrn-containing HindIII fragment was studied for 67 Escherichia coli neonatal meningitis strains, 58 E. coli K1 commensal strains, and 47 E. coli blood isolates from neonates without meningitis. ibe10, sfa, and the 14.9-kb HindIII fragment were observed significantly more often in the meningitis strains than in blood or commensal strains.

Full Text

The Full Text of this article is available as a PDF (107.9 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bingen E. H., Denamur E., Lambert-Zechovsky N. Y., Bourdois A., Mariani-Kurkdjian P., Cezard J. P., Navarro J., Elion J. DNA restriction fragment length polymorphism differentiates crossed from independent infections in nosocomial Xanthomonas maltophilia bacteremia. J Clin Microbiol. 1991 Jul;29(7):1348–1350. doi: 10.1128/jcm.29.7.1348-1350.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bingen E., Denamur E., Brahimi N., Elion J. Genotyping may provide rapid identification of Escherichia coli K1 organisms that cause neonatal meningitis. Clin Infect Dis. 1996 Jan;22(1):152–156. doi: 10.1093/clinids/22.1.152. [DOI] [PubMed] [Google Scholar]
  3. Bingen E., Denamur E., Lambert-Zechovsky N., Aujard Y., Brahimi N., Geslin P., Elion J. Analysis of DNA restriction fragment length polymorphism extends the evidence for breast milk transmission in Streptococcus agalactiae late-onset neonatal infection. J Infect Dis. 1992 Mar;165(3):569–573. doi: 10.1093/infdis/165.3.569. [DOI] [PubMed] [Google Scholar]
  4. Bortolussi R., Ferrieri P., Björkstén B., Quie P. G. Capsular K1 polysaccharide of Escherichia coli: relationship to virulence in newborn rats and resistance to phagocytosis. Infect Immun. 1979 Jul;25(1):293–298. doi: 10.1128/iai.25.1.293-298.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Cross A., Orskov I., Orskov F., Sadoff J., Gemski P. Identification of Escherichia coli K1 antigen. J Clin Microbiol. 1984 Aug;20(2):302–304. doi: 10.1128/jcm.20.2.302-304.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Huang S. H., Wass C., Fu Q., Prasadarao N. V., Stins M., Kim K. S. Escherichia coli invasion of brain microvascular endothelial cells in vitro and in vivo: molecular cloning and characterization of invasion gene ibe10. Infect Immun. 1995 Nov;63(11):4470–4475. doi: 10.1128/iai.63.11.4470-4475.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Korhonen T. K., Valtonen M. V., Parkkinen J., Väisänen-Rhen V., Finne J., Orskov F., Orskov I., Svenson S. B., Mäkelä P. H. Serotypes, hemolysin production, and receptor recognition of Escherichia coli strains associated with neonatal sepsis and meningitis. Infect Immun. 1985 May;48(2):486–491. doi: 10.1128/iai.48.2.486-491.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Korhonen T. K., Virkola R., Lähteenmäki K., Björkman Y., Kukkonen M., Raunio T., Tarkkanen A. M., Westerlund B. Penetration of fimbriate enteric bacteria through basement membranes: a hypothesis. FEMS Microbiol Lett. 1992 Dec 15;100(1-3):307–312. doi: 10.1111/j.1574-6968.1992.tb14057.x. [DOI] [PubMed] [Google Scholar]
  9. Le Bouguenec C., Archambaud M., Labigne A. Rapid and specific detection of the pap, afa, and sfa adhesin-encoding operons in uropathogenic Escherichia coli strains by polymerase chain reaction. J Clin Microbiol. 1992 May;30(5):1189–1193. doi: 10.1128/jcm.30.5.1189-1193.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ott M., Hacker J., Schmoll T., Jarchau T., Korhonen T. K., Goebel W. Analysis of the genetic determinants coding for the S-fimbrial adhesin (sfa) in different Escherichia coli strains causing meningitis or urinary tract infections. Infect Immun. 1986 Dec;54(3):646–653. doi: 10.1128/iai.54.3.646-653.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Parkkinen J., Korhonen T. K., Pere A., Hacker J., Soinila S. Binding sites in the rat brain for Escherichia coli S fimbriae associated with neonatal meningitis. J Clin Invest. 1988 Mar;81(3):860–865. doi: 10.1172/JCI113395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Quagliarello V. J., Scheld W. M. Recent advances in the pathogenesis and pathophysiology of bacterial meningitis. Am J Med Sci. 1986 Nov;292(5):306–309. doi: 10.1097/00000441-198611000-00010. [DOI] [PubMed] [Google Scholar]
  13. Robbins J. B., McCracken G. H., Jr, Gotschlich E. C., Orskov F., Orskov I., Hanson L. A. Escherichia coli K1 capsular polysaccharide associated with neonatal meningitis. N Engl J Med. 1974 May 30;290(22):1216–1220. doi: 10.1056/NEJM197405302902202. [DOI] [PubMed] [Google Scholar]
  14. Siitonen A., Takala A., Ratiner Y. A., Pere A., Mäkelä P. H. Invasive Escherichia coli infections in children: bacterial characteristics in different age groups and clinical entities. Pediatr Infect Dis J. 1993 Jul;12(7):606–612. doi: 10.1097/00006454-199307000-00012. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES