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. 1997 Dec;71(12):9833–9836. doi: 10.1128/jvi.71.12.9833-9836.1997

The published DNA sequence of human cytomegalovirus strain AD169 lacks 929 base pairs affecting genes UL42 and UL43.

D J Dargan 1, F E Jamieson 1, J MacLean 1, A Dolan 1, C Addison 1, D J McGeoch 1
PMCID: PMC230300  PMID: 9371656

Abstract

Compared with the published DNA sequence (M. S. Chee, et al. Curr. Top. Microbiol. Immunol. 154:125-170, 1990), most isolates of human cytomegalovirus strain AD169 contain an additional 929 bp after nucleotide 54612. This results in a changed reading frame for the 5'-terminal 50 codons of gene UL42 and expansion of gene UL43 (a US22 family member) from 187 (3'-truncated) to 423 (full-length) codons. The UL42 and UL43 gene products are nonessential for growth in culture.

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Selected References

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