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. 1997 Dec;71(12):9855–9858. doi: 10.1128/jvi.71.12.9855-9858.1997

Role of a single amino acid at the amino terminus of the simian virus 5 F2 subunit in syncytium formation.

M Ito 1, M Nishio 1, M Kawano 1, S Kusagawa 1, H Komada 1, Y Ito 1, M Tsurudome 1
PMCID: PMC230304  PMID: 9371660

Abstract

The fusion (F) protein of simian virus 5 (strain W3A) induced extensive cell fusion in BHK cells when expressed alone, while that of strain WR did not. Mutational analysis demonstrated that the fusing activity can be transferred to the WR F protein by a proline residue at position 22 of subunit W3A F2.

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Selected References

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