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. 1999 Sep;98(1):71–79. doi: 10.1046/j.1365-2567.1999.00844.x

Figure 2.

Figure 2

CH response in IL-4 KO mice can be restored by IL-4. IL-4 KO (○) and wt (•) mice were sensitized with TNCB and challenged 5 days later. Some groups of mice also received different amounts of IL-4 immediately before sensitization (upper panel) or immediately before challenge (lower panel). The increases in ear thickness were measured 24 hr after challenge. Mice that were not sensitized, but only challenged with TNCB (challenge only), gave the following results: IL-4 KO, 1·1±0·2; wt, 1·0±0·1. *P < 0·01 and **P < 0·001 as compared to the values detected in IL-4 KO mice.