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. 2000 Mar;99(3):451–457. doi: 10.1046/j.1365-2567.2000.00983.x

Figure 5.

Figure 5

Capacity of OVA injected intracamerally to induce ACAID in mice deficient in CD95 or CD95L expression. OVA was injected into the anterior chamber of one eye of panels of normal C57BL/6 mice, and of B6.lpr/lpr (a) or B6.gld/gld (b) mice. Seven days later these mice were immunized subcutaneously with OVA plus CFA. One week later their ear pinnae, as well as pinnae of naive (negative control) mice, were challenged with an injection of OVA. Positive controls were immunized with OVA and CFA s.c. 7 days prior to intrapinnae challenge with OVA. Ear swelling responses were measured 24 hr after challenge. Bars represent the mean± SE (n = 5). Asterisks indicate mean values significantly lower than positive controls (P < 0·05).