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. 1986 Apr;32:823–827.

A Clinical Approach to the Diagnosis of Acid-Base Disorders

Robert A Bear
PMCID: PMC2327641  PMID: 21267134

Abstract

The ability to diagnose and manage acid-base disorders rapidly and effectively is essential to the care of critically ill patients. This article presents an approach to the diagnosis of pure and mixed acid-base disorders, metabolic or respiratory. The approach taken is based on using the law of mass-action equation as it applies to the bicarbonate buffer system (Henderson equation), using sub-classifications for diagnostic purposes of causes of metabolic acidosis and metabolic alkalosis, and using a knowledge of the well-defined and predictable compensatory responses that attempt to limit the change in pH in each of the primary acid-base disorders.

Keywords: Acid-base disorders, diagnosis, acute care

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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