Abstract
A mutant of Escherichia coli K-12 carrying a deletion in the aroG-nadA region of the genome requires a high concentration of iron for growth. The strain is chromium sensitive, and in the presence of citrate lower concentrations of iron support cell growth. The deletion mutant lost a gene between aroG and nadA that is responsible for the uptake of iron.
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Selected References
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- Adhya S. L., Shapiro J. A. The galactose operon of E. coli K-12. I. Structural and pleiotropic mutations of the operon. Genetics. 1969 Jun;62(2):231–247. doi: 10.1093/genetics/62.2.231. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cox G. B., Gibson F., Luke R. K., Newton N. A., O'Brien I. G., Rosenberg H. Mutations affecting iron transport in Escherichia coli. J Bacteriol. 1970 Oct;104(1):219–226. doi: 10.1128/jb.104.1.219-226.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Frost G. E., Rosenberg H. Relationship between the tonB locus and iron transport in Escherichia coli. J Bacteriol. 1975 Nov;124(2):704–712. doi: 10.1128/jb.124.2.704-712.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Frost G. E., Rosenberg H. The inducible citrate-dependent iron transport system in Escherichia coli K12. Biochim Biophys Acta. 1973 Nov 30;330(1):90–101. doi: 10.1016/0005-2736(73)90287-3. [DOI] [PubMed] [Google Scholar]
- Langman L., Young I. G., Frost G. E., Rosenberg H., Gibson F. Enterochelin system of iron transport in Escherichia coli: mutations affecting ferric-enterochelin esterase. J Bacteriol. 1972 Dec;112(3):1142–1149. doi: 10.1128/jb.112.3.1142-1149.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Luke R. K., Gibson F. Location of three genes concerned with the conversion of 2,3-dihydroxybenzoate into enterochelin in Escherichia coli K-12. J Bacteriol. 1971 Aug;107(2):557–562. doi: 10.1128/jb.107.2.557-562.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shapiro J. A., Adhya S. L. The galactose operon of E. coli K-12. II. A deletion analysis of operon structure and polarity. Genetics. 1969 Jun;62(2):249–264. doi: 10.1093/genetics/62.2.249. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Somerville R. L. Epistasis between deletion mutations in the tryptophan region and mutations affecting the general aromatic pathway in Escherichia coli K-12. J Bacteriol. 1967 Nov;94(5):1798–1799. doi: 10.1128/jb.94.5.1798-1799.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wang C. C., Newton A. An additional step in the transport of iron defined by the tonB locus of Escherichia coli. J Biol Chem. 1971 Apr 10;246(7):2147–2151. [PubMed] [Google Scholar]
- Wang C. C., Newton A. Iron transport in Escherichia coli: relationship between chromium sensitivity and high iron requirement in mutants of Escherichia coli. J Bacteriol. 1969 Jun;98(3):1135–1141. doi: 10.1128/jb.98.3.1135-1141.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wang C. C., Newton A. Iron transport in Escherichia coli: roles of energy-dependent uptake and 2,3-dihydroxybenzoylserine. J Bacteriol. 1969 Jun;98(3):1142–1150. doi: 10.1128/jb.98.3.1142-1150.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Young I. G., Langman L., Luke R. K., Gibson F. Biosynthesis of the iron-transport compound enterochelin: mutants of Escherichia coli unable to synthesize 2,3-dihydroxybenzoate. J Bacteriol. 1971 Apr;106(1):51–57. doi: 10.1128/jb.106.1.51-57.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]