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. 1975 Apr;122(1):250–256. doi: 10.1128/jb.122.1.250-256.1975

Origin of the TEM-beta-lactamase gene found on plasmids.

F Heffron, R Sublett, R W Hedges, A Jacob, S Falkow
PMCID: PMC235664  PMID: 1091625

Abstract

A sequence of deoxyribonucleic acid of 2.7 times 10-6 to 3.3 times 10-6 daltons which includes the TEM beta-lactamase gene is present on the small plasmid RSF 1030 (R-Amp). This same sequence is present on plasmid derivatives that have received a translocation of deoxyribonucleic acid specifying the TEM beta-lactamase and is also present on naturally occurring plasmids of the F1, F11, N, X, O, I, C, and W incompatibility groups that do not specify ampicillin resistance or specify O-type beta-lactamases.

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Selected References

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